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Original paper Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer.

Cancer Cell International.， 2023； 23：57

DOI:10.1186/s12935-023-02904-y

Hayashi Y, Nakayama J, Yamamoto M, Maekawa M, Watanabe S, Higashiyama S, Inoue JI, Yamamoto Y, Semba K

Original paper Metabolic clogging of mannose triggers genomic instability via dNTP loss in human cancer cells

eLife.， 2023； 12：e83870

DOI:10.7554/eLife.83870

Harada Y, Mizote Y, Suzuki T, Nishida M, Hiratsuka T, Ueda A, Imagawa Y, Maeda K, Ohkawa Y, Murai M, Freeze H. H, Miyoshi E, Higashiyama S, Udono U, Dohmae N, Tahara H, Taniguchi N.

Original paper SPOP is essential for DNA replication licensing through maintaining translation of CDT1 and CDC6 in HaCaT cells.

Biochemical and Biophysical Research Communications.， 2023； 651(9)：30-38

DOI:10.1016/j.bbrc.2023.02.012

Sanada S, Maekawa M, Tate S, Nakaoka H, Fujisawa Y, Sayama K, Higashiyama S.

Original paper BCL6B Contributes to Ocular Vascular Diseases via Notch Signal Silencing

Arteriosclerosis, Thrombosis, and Vascular Biology.， 2023； 43：927-942

DOI:10.1161/ATVBAHA.123.318987

Tanaka M, Nakamura S, Sakaue T, Yamamoto T, Maekawa M, Nishinaka A, Yasuda H, Yunoki K, Sato Y, Sawa M, Yoshino K, Shimazawa M, Hatano M, Tokuhisa T, Higashiyama S, Hara H.

Original paper Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression.

Journal of Biological Chemistry.， 2023； 299：104826

DOI:10.1016/j.jbc.2023.104826

Sato S, Miyazaki M, Fukuda S, Mizutani Y, Mizukami Y, Higashiyama S, Inoue S

Original paper Reply: Low-Grade Inflammation: A Familiar Factor in Cardiovascular Diseases

JACC: Basic to Translational Science.， 2023； 8 (11)：1476

DOI:10.1016/j.jacbts.2023.09.009

Sakaue T and Izutani H

Original paper Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway

Nature Communications.， 2023； 14：7048

DOI:10.1038/s41467-023-42774-6

Nakai K, Lin H, Yamano S, Tanaka S, Kitamoto S, Saitoh H, Sakuma K, Kurauchi J, Akter E, Konno M, Ishibashi K, Kamata R, Ohashi A, Koseki J, Takahashi H, Yokoyama H, Shiraki Y, Enomoto A, Abe S, Hayakawa Y, Ushiku T, Mutoh M, Fujita Y, Kon S.

Original paper Utility of synthetic MRI in predicting pathological complete response of various breast cancer subtypes prior to neoadjuvant chemotherapy

Clin Radiol..， 2022； 2022 Aug 30：S0009-9260(22)00328-2

DOI:10.1016/j.crad.2022.06.019

M.Matsuda, N.Fukuyama, T.Matsuda, S.Kikuchi, Y.Shiraishi, Y.Takimoto, Y.Kamei, M.Kurata, R.Kitazawa, T.Kido

Original paper Triple-negative breast cancer on contrast-enhanced MRI and synthetic MRI: A comparison with non-triple-negative breast carcinoma

Eur J Radiol.， 2022； Sep;142：109838

DOI:10.1016/j.ejrad.2021.109838

Megumi Matsuda, Takaharu Tsuda, Rui Ebihara, Wataru Toshimori, Kanako Okada, Shiori Takeda, Aya Okumura, Yasuhiro Shiraishi, Hiroshi Suekuni, Yoshiaki Kamei, Mie Kurata, Riko Kitazawa, Teruhito Mochizuki, Teruhito Kido

Original paper Synthesis and photophysical properties of a new push–pull pyrene dye with green-to-far-red emission and its application to human cellular and skin tissue imaging

Journal of Materials Chemistry B.， 2022； 10：1641-1649

DOI:10.1039/D1TB02728J

Kazuki Inoue, Ryosuke Kawakami, Masamoto Murakami, Taku Nakayama, Shinkuro Yamamoto, Keiji Inoue, Teruko Tsuda, Koji Sayama, Takeshi Imamura, Daisuke Kaneno, Shingo Hadano, Shigeru Watanabe and Yosuke Niko

Original paper TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial–mesenchymal transition

Molecular Oncology.， 2022； 16(12)：2330-2354

DOI:10.1002/1878-0261.13215

Yutaro Tsubakihara, Yae Ohata, Yukari Okita, Shady Younis, Jens Eriksson, Mikael E. Sellin, Jiang Ren, Peter ten Dijke, Kohei Miyazono, Atsuhiko Hikita, Takeshi Imamura, Mitsuyasu Kato, Carl-Henrik Heldin, Aristidis Moustakas

Original paper Tumor-targeted fluorescence labeling systems for cancer diagnosis and treatment

Cancer Science.， 2022； 113(6)：1919-1929

DOI:10.1111/cas.15369

Hiroshi Tazawa, Kunitoshi Shigeyasu, Kazuhiro Noma, Shunsuke Kagawa, Fuminori Sakurai, Hiroyuki Mizuguchi, Hisataka Kobayashi, Takeshi Imamura, Toshiyoshi Fujiwara

Original paper Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut

Cell Reports.， 2022； 39(6)：110773

DOI:10.1016/j.celrep.2022.110773

Yusuke Yoshimatsu, Tomohisa Sujino, Kentaro Miyamoto, Yosuke Harada, Shun Tanemoto, Keiko Ono, Satoko Umeda, Kosuke Yoshida, Toshiaki Teratani, Takahiro Suzuki, Yohei Mikami, Nobuhiro Nakamoto, Nobuo Sasaki, Kaoru Takabayashi, Naoki Hosoe, Haruhiko Ogata, Kazuaki Sawada, Takeshi Imamura, Akihiko Yoshimura, Takanori Kanai,

Original paper Differences in interaction lead to the formation of different types of insulin amyloid

scientific reports.， 2022； 12：8556

DOI:10.1038/s41598-022-12212-6

Wakako Mori, Ryosuke Kawakami, Yosuke Niko, Tomohiro Haruta, Takeshi Imamura, Kentaro Shiraki & Tamotsu Zako

Original paper Computer-Aided Detection of Quantitative Signatures for Breast Fibroepithelial Tumors Using Label-Free Multi-Photon Imaging

Molecules.， 2022； 27(10)：3340

DOI:10.3390/molecules27103340

Kana Kobayashi-Taguchi, Takashi Saitou, Yoshiaki Kamei, Akari Murakami, Kanako Nishiyama, Reina Aoki, Erina Kusakabe, Haruna Noda, Michiko Yamashita, Riko Kitazawa, Takeshi Imamura and Yasutsugu Takada

Original paper Cell–matrix interface regulates dormancy in human colon cancer stem cells.

Nature.， 2022； 608：784–794

DOI:10.1038/s41586-022-05043-y

Yuki Ohta, Masayuki Fujii, Sirirat Takahashi, Ai Takano, Kosaku Nanki, Mami Matano, Hikaru Hanyu, Megumu

Original paper Identification of Quiescent LGR5+ Stem Cells in the Human Colon

Gastroenterology.， 2022； 163(5)：1391-1406.e24

DOI:10.1053/j.gastro.2022.07.081

Keiko Ishikawa, Shinya Sugimoto, Mayumi Oda, Masayuki Fujii, Sirirat Takahashi, Yuki Ohta, Ai Takano, Kazuhiro Ishimaru, Mami Matano, Kosuke Yoshida, Hikaru Hanyu, Kohta Toshimitsu, Kazuaki Sawada, Mariko Shimokawa, Megumu Saito, Kenta Kawasaki, Ryota Ishii, Koji Taniguchi, Takeshi Imamura, Takanori Kanai, Toshiro Sato,

Original paper NIR-II-Excitable Dye-Loaded Nanoemulsions for Two-Photon Microscopy Imaging of Capillary Blood Vessels in the Entire Hippocampal CA1 Region of Living Mice

ACS Applied Materials & Interfaces.， 2022； 14(36)：40481–40490

DOI:10.1021/acsami.2c03299

Hitomi Matsuura, Ryosuke Kawakami, Maki Isoe, Masaharu Hoshihara, Yuya Minami, Kazuki Yatsuzuka, Teruko Tsuda, Masamoto Murakami, Yasutaka Suzuki, Jun Kawamata, Takeshi Imamura, Shingo Hadano, Shigeru Watanabe, and Yosuke Niko

Original paper Identifying Targets of Protective Antibodies against Severe Malaria in Papua, Indonesia, Using Locally Expressed Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1

Infection and Immunity.， 2022； 90(2)：e0043521

DOI:10.1128/IAI.00435-21

Janavi S. Rambhatla, Gerry Q. Tonkin-Hill, Eizo Takashima, Takafumi Tsuboi, Rintis Noviyanti, Leily Trianty, Boni F. Sebayang, Daniel A. Lampah, Jutta Marfurt, Ric N. Price, Nicholas M. Anstey, Anthony T. Papenfuss, Timon Damelang, Amy W. Chung, Michael F. Duffy, Stephen J. Rogerson

Original paper The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes

Frontiers in Cell and Developmental Biology.， 2022； 10：884509

DOI:10.3389/fcell.2022.884509

Hamasaki E, Wakita N, Yasuoka H, Nagaoka H, Morita M, Takashima E, Uchihashi T, Takeda T, Abe T, Lee J-W, Iimura T, Saleem MA, Ogo N, Asai A, Narita A, Takei K and Yamada H