To the Future with
PROTEO-SCIENCE

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ABOUT PROS

Proteins are the building blocks of life. The wheat cell-free protein synthesis method, pioneered here at PROS, enables the high-throughput, large scale synthesis of high quality proteins.

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PRiME

PRiME is a joint-use, collaborative research center focusing on interactome analysis set up by the Proteo-Science Center at Ehime University.
Collaborative research is the bedrock of our center, and we are continuously adapting our program to facilitate our ability to work together with researchers all over the world.

DEPARTMENTS

The Proteo-Science Center at Ehime University consists of various diverse research departments affiliated with 'Fundamental Technology Development‘ and 'Complex Bioscience Analysis’. We aim to promote protein-based life science research, and to use our expertise to inform the development of novel diagnostics and therapeutics for the improvement of human health.

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ACHIEVEMENTS

Original paper Co-expression of CD30 and SLFN11 serves as a dual biomarker for the treatment of cutaneous T-cell lymphoma

NAR Cancer.., 2025; 7(4):zcaf037
DOI:https://doi.org/10.1093/narcan/zcaf037
Takatoshi Shimauchi, Junko Murai, Manami Iwasaki, Pawit Phadungsaksawasdi, Toshiyuki Ojima, Kazuyasu Fujii, Tetsuya Honda

Original paper Amino acid–dependent TSC2 dephosphorylation by lysosome–PP2A regulates mTORC1 signaling transduction

Life Science Alliance., 2025; vol8 no11:e202503206
DOI:10.26508/lsa.202503206
Takanori Nakamura , Shigeyuki Nada , Masaki Matsumoto , Nuha Loling Othman , Hidetaka Kosako , Kazuki Ikeda , Naohiko Koshikawa , Junya Masumoto , Tatsuya Sawasaki , Mutsuhiro Takekawa , Takashi Suzuki , Masato Okada

Original paper Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes.

Nat Commun.., 2025; 1:1
DOI:
Yanagihara Y, Takahashi M, Izumi Y, Kinoshita T, Takao M, Bamba T, Imai Y.

Original paper Extended Depth of Focus Two-photon Light-sheet Microscopy for in vivo Fluorescence Imaging of Large Multicellular Organisms at Cellular Resolution

International Journal of Molecular Sciences., 2025; 24 (12):10186
DOI:10.3390/ijms241210186
Takashi Saitou, Takeshi Imamura

Original paper Extended Depth of Focus Two-photon Light-sheet Microscopy for in vivo Fluorescence Imaging of Large Multicellular Organisms at Cellular Resolution

International Journal of Molecular Sciences., 2025; 24 (12):10186
DOI:10.3390/ijms241210186
Takashi Saitou, Takeshi Imamura