To the Future with
PROTEO-SCIENCE

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ABOUT PROS

Proteins are the building blocks of life. The wheat cell-free protein synthesis method, pioneered here at PROS, enables the high-throughput, large scale synthesis of high quality proteins.

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PRiME

PRiME is a joint-use, collaborative research center focusing on interactome analysis set up by the Proteo-Science Center at Ehime University.
Collaborative research is the bedrock of our center, and we are continuously adapting our program to facilitate our ability to work together with researchers all over the world.

DEPARTMENTS

The Proteo-Science Center at Ehime University consists of various diverse research departments affiliated with 'Fundamental Technology Development‘ and 'Complex Bioscience Analysis’. We aim to promote protein-based life science research, and to use our expertise to inform the development of novel diagnostics and therapeutics for the improvement of human health.

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ACHIEVEMENTS

Original paper Safety and efficacy of the anti-AGEs supplement d-Gs: A pilot study of AGEs improvement effect and safety review of anti-AGEs supplementation

Adv Integr Med.., 2026; 13(2):100638
DOI:10.1016/j.aimed.2026.100638
Igase M, Okada Y, Igase K, Imai Y, Miura S, Ochi M, Ohyagi Y, Yamagishi S

Original paper PHF2 regulates grip strength via demethylation at the promoter region of the Mef2c

iScience.., 2026; 29(4):115517
DOI:10.1016/j.isci.2026.115517
Fukushima T, Fujioka T, Imai Y, Masubuchi S, Sakakibara I

Original paper Nucleic acid detection based on single-cluster analysis of cross-linking aggregates of DNA-modified gold nanoparticles using a dark-field microscope

Anal. Sci.., 2026; 42:201-205
DOI:10.1007/s44211-026-00878-1
Yuki Tanaka, Nanami Fukuzumi, Gen Hirao, Atsushi Ogawa, Tsuyoshi Asahi, Mizuo Maeda, Tamotsu Zako

Original paper (日本語) Impact of oral eicosapentaenoic acid on veno-occlusive disease/sinusoidal obstruction syndrome onset prevention: single-center retrospective analysis

(日本語) Transplantation and Cellular Therapy., 2025; :
DOI:(日本語) doi: 10.1016/j.jtct.2025.10.004
(日本語) Miyazaki Y, Narumi H, Azuma T, Tanimoto K, Masuda Y, Kato J, Konishi T, Nabe S, Maruta M, Ochi T, Yamanouchi J, Takenaka K

Original paper (日本語) Bystander CAR-CD8+ T cells in a CAR-T cell product can expand and enhance the antitumor effects of a bispecific antibody

(日本語) Journal for Immunotherapy of Cancer,., 2025; (日本語) 13(6):
DOI:(日本語) doi: 10.1136/jitc-2025-011690
(日本語) Kato J, Konishi T, Honda T, Maruta M, Nabe S, Masuda Y, Matsumoto M, Kawasaki N, Miyazaki Y, Doi Y, Takasuka Y, Yamanouchi J, Ochi T, Takenaka K.