To the Future with
PROTEO-SCIENCE

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ABOUT PROS

Proteins are the building blocks of life. The wheat cell-free protein synthesis method, pioneered here at PROS, enables the high-throughput, large scale synthesis of high quality proteins.

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PRiME

PRiME is a joint-use, collaborative research center focusing on interactome analysis set up by the Proteo-Science Center at Ehime University.
Collaborative research is the bedrock of our center, and we are continuously adapting our program to facilitate our ability to work together with researchers all over the world.

DEPARTMENTS

The Proteo-Science Center at Ehime University consists of various diverse research departments affiliated with 'Fundamental Technology Development‘ and 'Complex Bioscience Analysis’. We aim to promote protein-based life science research, and to use our expertise to inform the development of novel diagnostics and therapeutics for the improvement of human health.

イメージ:研究部門

ACHIEVEMENTS

Original paper Tuning of the ChlD1 and ChlD2 properties in Photosystem II by site-directed mutagenesis of neighbouring amino acids

Biochim. Biophys. Acta (Bioenergetics)., 2023; *:*
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Sugiura, M., Kimura, M., Koyama, K., Nakamura, M., Shimamoto, N., Takegawa, Y., Sellés, J., Boussac, A., and Rutherford, A.W.

Original paper Absorption changes in Photosystem II in the Soret band region upon the formation of the chlorophyll cation radical [PD1PD2]+

Photosynth. Res.., 2023; *:*
DOI:
Boussac, A., Sugiura, M., Nakamura, M., Nagao, R., Noguchi, T., Viola, S., Rutherford, A.W., and Sellés, J.

Original paper Rational design of eukaryotic riboswitches that upregulate IRES-mediated translation initiation with high switching efficiency through a kinetic trapping mechanism in vitro

RNA., 2023; **:***
DOI:10.1261/rna.079778.123
Hajime Takahashi, Masahiro Fujikawa, Atsushi Ogawa

Original paper Identification of novel Plasmodium vivax proteins associated with protection against clinical malaria

Frontiers in Cellular and Infection Microbiology., 2022; 13:
DOI:10.3389/fcimb.2023.1076150
Ramin Mazhari, Eizo Takashima, Rhea J. Longley, Shazia Ruybal-Pesantez, Michael T. White, Bernard N. Kanoi, Hikaru Nagaoka, Benson Kiniboro, Peter Siba, Takafumi Tsuboi, Ivo Mueller

Original paper Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of Plasmodium vivax gametocytes to Anopheles arabiensis mosquitoes

Frontiers in Cellular and Infection Microbiology., 2022; 12:
DOI:10.3389/fcimb.2022.1106369
Surafel K. Tebeje, Wakweya Chali, Elifaged Hailemeskel, Jordache Ramjith, Abrham Gashaw, Temesgen Ashine, Desalegn Nebret, Endashaw Esayas, Tadele Emiru, Tizita Tsegaye, Karina Teelen, Kjerstin Lanke, Eizo Takashima, Takafumi Tsuboi, Nichole D. Salinas, Niraj H. Tolia, David Narum, Chris Drakeley, Benoit Witkowski, Amelie Vantaux, Matthijs M. Jore, William J. R. Stone, Ivo S. Hansen, Fitsum G. Tadesse, Teun Bousema