To the Future with
PROTEO-SCIENCE

イメージ:
イメージ:
イメージ:
イメージ:
イメージ:

ABOUT PROS

Proteins are the building blocks of life. The wheat cell-free protein synthesis method, pioneered here at PROS, enables the high-throughput, large scale synthesis of high quality proteins.

イメージ:
イメージ:
イメージ:
イメージ:
イメージ:

PRiME

PRiME is a joint-use, collaborative research center focusing on interactome analysis set up by the Proteo-Science Center at Ehime University.
Collaborative research is the bedrock of our center, and we are continuously adapting our program to facilitate our ability to work together with researchers all over the world.

DEPARTMENTS

The Proteo-Science Center at Ehime University consists of various diverse research departments affiliated with 'Fundamental Technology Development‘ and 'Complex Bioscience Analysis’. We aim to promote protein-based life science research, and to use our expertise to inform the development of novel diagnostics and therapeutics for the improvement of human health.

イメージ:研究部門

ACHIEVEMENTS

Original paper New insights into the involvement of residue D1-V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus

Biochim. Biophys. Acta (Bioenergetics)., 2025; *:*
DOI:
Boussac, A., Sellés, J., Sugiura, M., and Burnap, R.L.

Original paper Micrometer-sized liposomes self-aggregate by forming DNA duplexes on their surfaces more sensitively than metallic nanoparticles

Chem. Lett.., 2025; 54:upaf012
DOI:10.1093/chemle/upaf012
Atsushi Ogawa, Ichiro Enomoto, Hajime Takahashi

Original paper HERC3 provides an ERAD branch for select membrane proteins by recognizing membrane-spanning domains.

J Cell Biol.., 2024; 223:e202308003
DOI:10.1083/jcb.202308003
Kamada Y, Ohnishi Y, Nakashima C, Fujii A, Terakawa M, Hamano I, Nakayamada U, Katoh S, Hirata N, Tateishi H, Fukuda R, Takahashi H, Lukacs GL, Okiyoneda T.

Original paper Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a α-furanosyl hemiketal of substrates

Sci. Rep.., 2024; 14:14602
DOI:10.1038/s41598-024-65627-8.
M. Akagashi, S. Watanabe, S. Kwiatkowski, J. Drozak, S. Terawaki, Y. Watanabe

Original paper pidermal growth factor receptor contributes to indirect regulation of skeletal muscle mass by androgen

Endocr J.., 2024; EJ24:0410
DOI:10.1507/endocrj.EJ24-0410
Onishi T, Sakai H, Uno H, Sakakibara I, Uezumi A, Honda M, Kai T, Higashiyama S, Miura N, Kikugawa T, Saika T, Imai Y.