Achievements

Original paper Long-term Nlrp3 gain-of-function mutation promotes cardiac dysfunction independent of inflammasome in mice

The Journal of Immunology.， 2026； 215(10)：vkag257

DOI:10.1093/jimmun/vkag257

Mie Kurata , Kayo Takahashi , Naoe Kaneko , Kenji Kameda , Takanori Nakamura , Sho Hosokawa , Kasumi Murakami , Hideki Ogura , Satoshi Ishido , Osamu Yamaguchi , Junya Masumoto

Original paper Structural and functional analysis of a photosystem II mutant PsbA3-S264V

Biochim. Biophys. Acta (Bioenergetics).， 2026； 1867：149607

DOI:10.1016/j.bbabio.2026.149607

Songbo, F., Nakajima, Y., Kato, K., Jiang. H., Tsai, P.-C-, Jia A., Sugiura, M. and Shen, J.R.

Original paper Cryo-EM structure of photosystem II D1-V185T mutant from Thermosynechococcus vestitus

Biochim. Biophys. Acta (Bioenergetics).， 2026； 1867：149598

DOI:10.1016/j.bbabio.2026.149598

Jiang, H., Nakajima, Y., Akita, F., Li, H., Kato, K., Sugiura, M., and Shen, J.-R.

Original paper Stage-specific expression and localization of ETRAMP4 during gametocyte development in the malaria parasite Plasmodium falciparum

Parasitology International.， 2026； 117：103390

DOI:10.1016/j.parint.2026.103390

H Iriko, A Omoda, H Aoi, M Tachibana, T Ishino, H Otsuki, T Tsuboi

Original paper Theophylline-dependent synthetic riboswitches enable tightly regulated inducible gene expression in tobacco plastids

Plant Biotechnol..， 2026； 43：333-341

DOI:10.5511/plantbiotechnology.26.0622a

Rika Yamane, Atsushi Ogawa, Takashi Shiina, Yuzuru Tozawa, Yoichi Nakahira

Original paper METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

FASEB J..， 2026； 40(17)：e72224

DOI:10.1096/fj.202600392R

Kasai F, Kim JD, Kako K, Muromachi N, Saito T, Yuan Y, Mizukami H, Kishikawa N, Nakamura K, Motomura K, Daitoku H, Imai Y, Sekiguchi S, Horiguchi K, Narumi S, Yamada M, Fukamizu A.

Original paper Potential Targets of Naturally Acquired Plasmodium vivax Transmission – Reducing Antibodies

Journal of Infection.， 2026； 93(3)：106833

DOI:10.1016/j.jinf.2026.106833

Rojrung R, Thongpoon S, Yuguchi T, Roobsoong W, Nagaoka H, Nguitragool W, Kanoi BN, Chotirat S, Tachibana M, Cui L, Ishino T, Miura K, Tsuboi T, Sattabongkot J, Takashima E.

Original paper Corisin induces proteostasis stress to drive epithelial injury and pulmonary fibrosis.

Nat Commun..， 2026； 17：8486

DOI:10.1038/s41467-026-76162-7

Fujimoto H, Yasuma T, D'Alessandro-Gabazza CN, Toda M, Nishihama K, Takeshita A, Fridman D'Alessandro V, Tomaru A, Saiki H, Okano T, Kogue Y, Anoh T, Alhawsawi MAB, Abdel-Hamid AM, Imai B, Fields CJ, Teofanovic J, Leistikow K, Ono R, Nosaka T, Yamazaki H, Yamakawa D, Bando YK, Sugihara F, Kikuta J, Kataoka K, Kondoh Y, Sakaue T, Takeda H, Yano Y, Hataji O, Cann I, Kobayashi T, Gabazza EC.

Original paper Alkyne Two-Phase Strategy: Rapid Generation of TK-285-Derived PROTACs as BRD4 Degraders.

J Med Chem..， 2026； 69：8388-8416

DOI:10.1021/acs.jmedchem.5c03771

Yamakoshi H, Watanabe R, Segawa R, Ishihara R, Tachibana R, Kudo G, Nagasawa S, Yamanaka S, Ito A, Takeda H, Sawasaki T, Yoshino R, Hirokawa T, Doi T, Hirasawa N, Iwabuchi Y.

Original paper Design of Analytical Methods for Protein Adsorption Characteristics at Material Interfaces.

Langmuir.， 2026； 42：17363-17374

DOI:10.1021/acs.langmuir.6c00943

Tanaka K, Nakano Y, Suganuma M, Matsumoto K, Hasegawa T, Nakahara M, Suto K, Ejima D, Imoarai T, Takeda H.

Original paper A lysine-free REC tag system for proximity-biotinylation applications.

Sci Rep..， 2026； 16：4846

DOI:10.1038/s41598-026-35323-w

Tokunaga S, Nagaoka H, Ozawa T, Yamada K, Takeda H, Fujisaki H, Hamada M, Soga F, Kishi H, Takashima E, Sawasaki T.

Original paper Screening and Engineering of Ancestral Sortase Es That Enable High-Fidelity Enzyme Design with Activity Trade-Off.

Bioconjug Chem..， 2026； 37：341-350

DOI:10.1021/acs.bioconjchem.5c00576

Koshiba R, Chisuga T, Fujinami D, Takeda H, Nakano S.

Original paper Face Mask-Wearing Behaviour Among Young Adults During and After the COVID-19 Epidemic in China

Asia Pac J Public Health.， 2026； 38(4)：332-335

DOI:10.1177/10105395261433224

Tao Z, Fang R, Ma T, Jiang W, Xia H, Culleton R, Jiao Y.

Original paper Saptiotemporal regulation of MKK4 dictates switch-like JNK activation and binary cell-fate decisions.

Nature Communications.， 2026； 17：1-18

DOI:10.1038/s41467-025-67943-7

Hisashi Moriizumi, Takanori Nakamura, Yuji Kubota, Ryosuke Hiranuma, Youngmin Cho, Toru Kawanishi, Hiroyuki Takeda, Takashi Suzuki, Mutsuhiro Takekawa

Original paper An autopsy case of multiple liver metastases from minute pancreatic acinar cell carcinoma clinically diagnosed as primary hepatic acinar cell carcinoma.

Clinical Journal of Gastroenterology..， 2026； 19：413-422

DOI:10.1007/s12328-026-02283-7

Okujima, Y., Tada, F., Murakami, H., Miyaoka, H., Kurata, M., & Masumoto, J

Original paper Macrophage accumulation on the injured pulmonary surface promotes intrathoracic adhesions.

Signal Transduction and Targeted Therapy..， 2026； 11：1-3

DOI:10.1038/s41392-026-02762-w

Mori, Y., Sakaue, T., Okazaki, M., Kurata, M., & Izutani, H.

Original paper Novel biodegradable device for transcatheter closure of atrial septal defects.

Scientific Reports..， 2026； 16：1-9

DOI:10.1038/s41598-026-48868-7

Kurobe, H., Sakaue, T., Hirata, Y., Moritani, T., Kurata, M., Higaki, T., & Shinoka, T.

Original paper Caldesmon-1-mediated actin dynamics is essential for osteogenic differentiation of aortic valve interstitial cells.

Scientific Reports.， 2026； 16：1-16

DOI:10.1038/s41598-026-39938-x

Komoda, M., Sakaue, T., Nakao, Y., Sakamoto, H., Fukunishi, T., Higaki, T., Aono, J., Kurobe, H., Kurata, M., Nishimura, T., & Izutani, H.

Original paper Diagnostic performance of kinetic parameters of ultrafast breast MRI and their associations with immunohistopathological findings of breast carcinoma.

Scientific Reports..， 2026； 16：1-14

DOI:10.1038/s41598-026-55998-5

Kobayashi, A., Matsuda, M., Okada, K., Matsuda, T., Ebihara, R., Ochi, H., Kawaguchi, N., Shiraishi, Y., Takimoto, Y., Ihara, Y., Kamei, Y., Kurata, M., Kitazawa, R., & Kido, T.

Original paper Spatial transcriptomics of urothelial carcinoma with basal/squamous differentiation identifies Galectin-7 as a specific marker of squamous lineage commitment. Discover.

Discov Oncol.， 2026； 17：722

DOI:10.1007/s12672-026-04927-z

Haga, S., Watanabe, R., Kurata, M., Miura, N., Liu, S., Kikugawa, T., Kitazawa, R., Mogi, M., & Saika, T.

ACHIEVEMENTS

SEARCH ACHIEVEMENTS