ACHIEVEMENTS

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英文原著 Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease

Nat Genet.., 2026; 58(7):1530-1545
DOI:10.1038/s41588-026-02640-9
Chai RC, Lundberg M, Freudenthal B, Smith JT, Boughton AP, Zhang Y, Flynn KA, Frysz M, Corr AP, Khoo WH, Komla-Ebri D, Dack MRG, Guilfoyle SE, Logan JG, Butterfield NC, Leitch VD, Pollard AS, Mäkitie RE, Bradford N, Ramos-Mucci L, Vilas-Zornoza A, Chen Y, Yip RKH, Er J, Tan SZ, McDonald MM, Youlten SE, Sergio CM, Castro-Martinez A, Young SG, Skorokhodova E, Evans DM, Powell JE, de Leeuw CA, Ewing AD, Eisman JA, Blank RD, Phan TG; International Federation of Musculoskeletal Research Societies (IFMRS) Big Data Working Group; Lagendijk AK, Hawkins ED, Oh HL, McIntyre RE, Hessel EM, Taylor-King JP, Baldock PA, Duncan EL, Williams GR, Bassett JHD, Croucher PI, Kemp JP.

英文原著 S100A4-TLR4-TGF-β axis as a therapeutic target for Dupuytren’s contracture in diabetic patients

Cell Death Discov.., 2026; 12:310
DOI:10.1038/s41420-026-03167-y
Kato K, Komura S, Yanagihara Y, Saeki N, Goto A, Maki R, Hirose H, Hirakawa A, Imai Y, Akiyama H.

英文原著 Ldha Regulates Osteosarcoma Lung Metastasis through Hedgehog Signaling

Cancer Res Commun.., 2026; 6(6):1495-1508
DOI:10.1158/2767-9764.CRC-25-0163
Maki R, Komura S, Nagano A, Niwa A, Tomita H, Imai Y, Akiyama H.

英文原著 A pleckstrin homology domain protein is involved in crystalloid formation in Plasmodium ookinetes and affects the maturation of infective sporozoites

oop Logo Frontiers in Cellular and Infection Microbiology., 2026; 16:2026
DOI:10.3389/fcimb.2026.1777159
Mayumi Tachibana, Naoaki Shinzawa, Minami Baba, Motomi Torii, Richard Culleton, Tomoko Ishino

英文原著 UNC45B Reduction With Aging: A Myofiber-Intrinsic Promoting Factor for Sarcopenia

Aging Cell.., 2026; 25(5):e70502
DOI:10.1111/acel.70502
Mishima T, Nagamune T, Tada S, Watanabe D, Tokuda N, Yamada T, Hashimoto-Hachiya A, Higo-Yamamoto S, Kido K, Nagaoka N, Ikedo A, Imai Y, Fujita R, Mizuno S, Takahashi S, Oishi K, Ato S, Ogasawara R.

英文原著 Integrating Scientific English and Life Science Learning to Foster Global Competence among High School Students

科学教育研究センター紀要., 2026; 5:6-12
DOI:
Kato A, Culleton R, Vergin R

英文原著 Identification of a novel rhoptry protein expressed predominantly in Plasmodium sporozoites

Frontiers in Cellular and Infection Microbiology., 2026; 15:1749149
DOI:10.3389/fcimb.2025.1749149
Oundavong S, Sekine T, Torii M, Ozawa T, Kosako H, Shinzawa N, Ishino T

英文原著 Development and Evaluation of Novel Zein-1 Based Artemisinin Sustained-Release Formulation for Treating Drug-Resistant Malaria

mBio., 2026; 17(2):e0369625
DOI:10.1128/mbio.03696-25
Wang Y, Yu X, Zhang X, He X, Tang Y, Fang L, Culleton R, Zhang Q, Dong W, Cao J

英文原著 Safety and efficacy of the anti-AGEs supplement d-Gs: A pilot study of AGEs improvement effect and safety review of anti-AGEs supplementation

Adv Integr Med.., 2026; 13(2):100638
DOI:10.1016/j.aimed.2026.100638
Igase M, Okada Y, Igase K, Imai Y, Miura S, Ochi M, Ohyagi Y, Yamagishi S

英文原著 PHF2 regulates grip strength via demethylation at the promoter region of the Mef2c

iScience.., 2026; 29(4):115517
DOI:10.1016/j.isci.2026.115517
Fukushima T, Fujioka T, Imai Y, Masubuchi S, Sakakibara I

英文原著 Nucleic acid detection based on single-cluster analysis of cross-linking aggregates of DNA-modified gold nanoparticles using a dark-field microscope

Anal. Sci.., 2026; 42:201-205
DOI:10.1007/s44211-026-00878-1
Yuki Tanaka, Nanami Fukuzumi, Gen Hirao, Atsushi Ogawa, Tsuyoshi Asahi, Mizuo Maeda, Tamotsu Zako

英文原著 Impact of oral eicosapentaenoic acid on veno-occlusive disease/sinusoidal obstruction syndrome onset prevention: single-center retrospective analysis

Transplantation and Cellular Therapy., 2025; :
DOI:doi: 10.1016/j.jtct.2025.10.004
Miyazaki Y, Narumi H, Azuma T, Tanimoto K, Masuda Y, Kato J, Konishi T, Nabe S, Maruta M, Ochi T, Yamanouchi J, Takenaka K

英文原著 Bystander CAR-CD8+ T cells in a CAR-T cell product can expand and enhance the antitumor effects of a bispecific antibody

Journal for Immunotherapy of Cancer,., 2025; 13(6):
DOI:doi: 10.1136/jitc-2025-011690
Kato J, Konishi T, Honda T, Maruta M, Nabe S, Masuda Y, Matsumoto M, Kawasaki N, Miyazaki Y, Doi Y, Takasuka Y, Yamanouchi J, Ochi T, Takenaka K.

英文原著 Antibody responses in Burkinabe children against P. falciparum proteins associated with reduced risk of clinical malaria.

Front Immunol.., 2025; :
DOI:
Yuguchi T, Dankyi BO, Rojrung R, Nagaoka H, Kanoi BN, Tiono AB, Nebie I, Ouedraogo A, Miura K, Sattabongkot J, Sirima SB, Tsuboi T, Takashima E

英文原著 Advances in transmission-blocking vaccines against Plasmodium falciparum and Plasmodium vivax.

Expert Rev Vaccines.., 2025; :
DOI:
Tachibana M, Takashima E, Torii M, Wu Y, Sattabongkot J, Tsuboi T.

英文原著 Exploring the P. falciparum antigens associated with reduced risk of malaria in pregnancy.

Front Immunol.., 2025; :
DOI:
Mwai L, Musundi S, Waweru H, Nagaoka H, Limbua PG, Tsuboi T, Takashima E, Gitaka J, Kanoi BN.

英文原著 Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex.

Science., 2025; :
DOI:
Dietrich MH, Chmielewski J, Chan LJ, Tan LL, Adair A, Lyons FMT, Gabriela M, Lopaticki S, Dite TA, Dagley LF, Pazzagli L, Gupta P, Kamil M, Vaughan AM, Rojrung R, Abraham A, Mazhari R, Longley RJ, Zeglinski K, Gouil Q, Mueller I, Fabb SA, Shandre-Mugan R, Pouton CW, Glukhova A, Shakeel S, Tham WH.

英文原著 Structure of endogenous Pfs230:Pfs48/45 in complex with six antibodies reveals mechanisms of malaria transmission-blocking activity

Immunity., 2025; :
DOI:doi: 10.1016/j.immuni.2025.09.014.
Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWT, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP

英文原著 Increased Plasmodium falciparum EBA175RIII-V antibody titres despite a 13-month malaria mass testing, treatment, and tracking intervention in a high malaria endemic community in Ghana.

Malar J., 2025; :
DOI:doi: 10.1186/s12936-025-05514-3
Tey PK, Brashear A, Kwapong SS, Acquah FK, Bredu DG, Busayomi A, Anang SF, Abban BC, Nagaoka H, Takashima E, Obiri-Yeboah D, Cui L, Amoah LE

英文原著 Plasmodium falciparum Liver Stage Antigen 3 plays a role in completing the final stages of merozoite invasion of red blood cells.

The Journal of Infectious Diseases., 2025; :
DOI:
Morita M, Jennison C, O’Neill MT, Kanoi BN, Ishino T, Tsuboi T, Boddey JA, Takashima E