Achievements

Original paper OsMYC2, an essential factor for JA-inductive sakuranetin production in rice, interacts with MYC2-like proteins that enhance its transactivation ability.

Sci Rep..， 2017； 7：40175

DOI:10.1038/srep40175

Ogawa S, Miyamoto K, Nemoto K, Sawasaki T, Yamane H, Nojiri H, Okada K.

Original paper Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

Proc Natl Acad Sci USA.， 2017； 114：3515-3520

DOI:10.1073/pnas.1615875114

Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O'Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ

Original paper Antibody responses to Plasmodium falciparum and Plasmodium vivax and prospective risk of Plasmodium spp. infection postpartum

Am J Trop Med Hyg.， 2017； 96：1197-1204

DOI:10.4269/ajtmh.16-0690

McLean ARD, Boel ME, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJI

Original paper Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

Sci Rep..， 2017； 7：46086

DOI:10.1038/srep46086

Morita M, Takashima E*, Ito D, Miura K, Thongkukiatkul A, Diouf A, Fairhurst RM, Diakite M, Long CA, Torii M, Tsuboi T

Original paper Plant Aurora kinases interact with and phosphorylate transcription factors.

J Plant Res..， 2016； 129：1165-1178

DOI:10.1007/s10265-016-0860-x

Takagi M, Sakamoto T, Suzuki R, Nemoto K, Obayashi T, Hirakawa T, Matsunaga TM, Kurihara D, Nariai Y, Urano T, Sawasaki T, Matsunaga S.

Original paper Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda

Vaccine.， 2017； 35：873-881

DOI:10.1016/j.vaccine.2017.01.001

Kanoi BN, Takashima E, Morita M, White MT, Palacpac NM, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T

Original paper Absence of in vivo selection for K13 mutations after artemether-lumefantrine treatment in Uganda.

Malar J..， 2017； 16：23

DOI:10.1186/s12936-016-1663-1

Balikagala B, Mita T, Ikeda M, Sakurai M, Yatsushiro S, Takahashi N, Tachibana SI, Auma M, Ntege EH, Ito D, Takashima E, Palacpac NM, Egwang TG, Onen JO, Kataoka M, Kimura E, Horii T, Tsuboi T

Original paper Functional characterization of Plasmodium berghei PSOP25 during ookinete development and as a malaria transmission-blocking vaccine candidate.

Parasit Vectors.， 2017； 10：8

DOI:10.1186/s13071-016-1932-4

Zheng W, Liu F, He Y, Liu Q, Humphreys GB, Tsuboi T, Fan Q, Luo E, Cao Y, Cui L

Original paper Co-administration of Systemic Zoledronate Promotes Osteogenesis Induced by a Local Co-delivery of Recombinant Human Bone Morphogenetic Protein-2 and β-tricalcium Phosphate in the Bone Marrow of the Rabbit Femur

J Musculoskelet Res..， 2017； 19(3)：1650015

DOI:10.1142/S0218957716500159

Mamoto K, Ohta Y, Ichikawa K, Imai Y, Minoda Y, Takaoka K, Nakamura H.

Original paper Ligand-responsive upregulation of 3′ CITE-mediated translation in a wheat germ cell-free expression system

Mol. BioSyst..， 2017； 13：314-319

DOI:10.1039/C6MB00748A

Ogawa A, Murashige Y, Tabuchi J, Omatsu T

Original paper Menin plays a critical role in the regulation of the antigen-specific CD8+ T cell response upon listeria infection.

J.Immunol..， 2017； 197：4079-4089

DOI:10.4049/jimmunol.1502295

Yamada T., Kanoh M., Nabe S., Yasuoka T., Suzuki J., Matsumoto A., Kuwahara M., Maruyama S., Fujimoto T., Sakisuka R., Yasukawa M., and Yamashita M.

Original paper Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes

Cell Host Microbe.， 2016； 20：618-630

DOI:10.1016/j.chom.2016.10.015

Bargieri DY, Thiberge S, Tay CL, Carey AF, Rantz A, Hischen F, Lorthiois A, Straschil U, Singh P, Singh S, Triglia T, Tsuboi T, Cowman A, Chitnis C, Alano P, Baum J, Pradel G, Lavazec C, Ménard R

Original paper Serological markers to measure recent changes in malaria at population level in Cambodia

Malar J..， 2016； 15：529

DOI:10.1186/s12936-016-1576-z

Kerkhof K, Sluydts V, Willen L, Kim S, Canier L, Heng S, Tsuboi T, Sochantha T, Sovannaroth S, Ménard D, Coosemans M, Durnez L

Original paper Identification of Plasmodium falciparum reticulocyte binding protein homologue 5-interacting protein, PfRipr, as a highly conserved blood-stage malaria vaccine candidate

Vaccine.， 2016； 34：5612-5622

DOI:10.1016/j.vaccine.2016.09.028

Ntege EH, Arisue N, Ito D, Hasegawa T, Palacpac NM, Egwang TG, Horii T, Takashima E, Tsuboi T

Original paper Plasmodium vivax GPI-anchored micronemal antigen (PvGAMA) binds human erythrocytes independent of Duffy antigen status

Sci Rep..， 2016； 6：35581

DOI:10.1038/srep35581

Cheng Y, Lu F, Wang B, Li J, Han JH, Ito D, Kong DH, Jiang L, Wu J, Ha KS, Takashima E, Sattabongkot J, Cao J, Nyunt MH, Kyaw MP, Desai SA, Miller LH, Tsuboi T, Han ET

Original paper The association between naturally acquired IgG subclass specific antibodies to the PfRH5 invasion complex and protection from Plasmodium falciparum malaria

Sci Rep..， 2016； 6：33094

DOI:10.1038/srep33094

Weaver R, Reiling L, Feng G, Drew DR, Mueller I, Siba PM, Tsuboi T, Richards JS, Fowkes FJ, Beeson JG

Original paper Proteomics-based analysis of lung injury-induced proteins in a mouse model of common bile duct ligation

Surgery.， 2017； S0039-6060(16)：30875-3.

DOI:10.1016/j.surg.2016.12.017

Sakaue T, Shikata F, Utsunomiya K, Fukae S, Kurata M, Nakaoka H, Okazaki M, Kawanishi Y, Kojima A, Higashiyama S, Izutani H

Original paper The intragraft microenvironment as a central determinant of chronic rejection or local immunoregulation/tolerance.

Current Opinion in Organ Transplantation.， 2017； 22：55-63

DOI:10.1097/MOT.0000000000000373

Wedel J, Nakayama H, Kochupurakkal NM, Koch J, Klagsbrun M, Dielenberg DR, Briscoe DM

Original paper Neddylated Cullin 3 is required for vascular endothelial-cadherin-mediated endothelial barrier function.

Cancer Sci.， 2017； 108：208-215

DOI:10.1111/cas.13133

Sakaue T, Fujisaki A, Nakayama H, Maekawa M, Hiyoshi H, Kubota E, Joh T, Izutani H, Higashiyama S.

Original paper Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.

Biochim Biophys Acta..， 2016； 1863(11)：2795-2808

DOI:10.1016/j.bbamcr.2016.09.002

Groth E, Pruessmeyer J, Babendreyer A, Schumacher J, Pasqualon T, Dreymueller D, Higashiyama S, Lorenzen I, Grötzinger J, Cataldo D, Ludwig A.

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