Achievements

Original paper Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling.

Biochem Biophys Res Commun..， 2020； 524(1)：44568

DOI:10.1016/j.bbrc.2019.12.049

Yamanaka S, Sato Y, Oikawa D, Goto E, Fukai S, Tokunaga F, Takahashi H, Sawasaki T.

Original paper Raf-like kinases CBC1 and CBC2 negatively regulate stomatal opening by negatively regulating plasma membrane H+-ATPase phosphorylation in Arabidopsis.

Photochem Photobiol Sci..， 2020； 19：88-98

DOI:10.1039/c9pp00329k

Hayashi M, Sugimoto H, Takahashi H, Seki M, Shinozaki K, Sawasaki T, Kinoshita T, Inoue SI.

Original paper Micro-CT imaging analysis for the effects of ibandronate and eldecalcitol on secondary osteoporosis and arthritis in adjuvant-induced arthritis rats.

Biomed Res..， 2019； 40(5)：197-205

DOI:10.2220/biomedres.40.197

Ono Y, Miyakoshi N, Kasukawa Y, Imai Y, Nagasawa H, Tsuchie H, Akagawa M, Nagahata I, Yuasa Y, Sato C, Kawatani M, Shimada Y.

Original paper Skeleton binding protein 1 (SBP1) of Plasmodium falciparum accumulates in electron-dense material before passing through the parasitophorous vacuole membrane

Parasitology International.， 2020； 75：102003

DOI:10.1016/j.parint.2019.102003

Hideyuki Iriko, Tomoko Ishino, Mayumi Tachibana, Ayaka Omoda, Motomi Torii, Takafumi Tsuboi

Original paper Observation of Morphological Changes of Female Osmiophilic Bodies Prior to Plasmodium Gametocyte Egress From Erythrocytes

Molecular and Biochemical Parasitology.， 2020； 236：111261

DOI:10.1016/j.molbiopara.2020.111261

Tomoko Ishino, Mayumi Tachibana, Minami Baba, Hideyuki Iriko, Takafumi Tsuboi, Motomi Torii

Original paper A Novel Plasmodium Yoelii Pseudokinase, PypPK1, Is Involved in Erythrocyte Invasion and Exflagellation Center Formation

Parasitology International.， 2020； 76：102056

DOI:10.1016/j.parint.2020.102056

Takahiro Ishizaki, Nattawat Chaiyawong, Hassan Hakimi , Masahito Asada, Mayumi Tachibana, Tomoko Ishino, Kazuhide Yahata, Osamu Kaneko

Original paper CF-PA2Vtech: a cell-free human protein array technology for antibody validation against human proteins

Sci Rep..， 2019； 9：19349

DOI:10.1038/s41598-019-55785-5

Morishita R, Sugiyama S, Denda M, Tokunaga S, Kido K, Shioya R, Ozawa S, Sawasaki T.

Original paper Automated collective motion analysis validates human keratinocyte stem cell cultures.

Sci Rep..， 2019； 9(1)：18725

DOI:10.1038/s41598-019-55279-4

Kinoshita K, Munesue T, Toki F, Isshiki M, Higashiyama S, Barrandon Y, Nishimura EK, Yanagihara Y, Nanba D.

Original paper Multiple strategies for heat adaptation to prevent chalkiness in the rice endosperm

Journal of Experimental Botany.， 2019； 70(4)：1299-1311

DOI:10.1093/jxb/ery427

Wada, H., Hatakeyama, Y., Onda, Y., Nonami, H., Nakashima, T., Erra-Balsells, R., Morita, S., Hiraoka, K., Tanaka, F., Nakano, H.

Original paper Component Profiling in Agricultural Applications Using an Adjustable Acupuncture Needle for Sheath-Flow Probe Electrospray Ionization/Mass Spectrometry

Journal of Agricultural and Food Chemistry.， 2019； 67 (11)：3275-3283

DOI:10.1021/acs.jafc.8b06424

Hiraoka, K., Rankin-Turner, S., Ninomiya, S., Wada, H., Nakano, H., Matsumura, M., Sanada-Morimura, S., Tanaka, F., Nonami, H.

Original paper Quantitative assay of targeted proteome in tomato trichome glandular cells using a large-scale selected reaction monitoring strategy

Plant Methods.， 2019； 15(1)：art. no. 40

DOI:10.1186/s13007-019-0427-7

Takemori, A., Nakashima, T., Ômura, H., Tanaka, Y., Nakata, K., Nonami, H., Takemori, N.

Original paper Direct comparison of target-reactivity and cross-reactivity induced by CAR- and BiTE-redirected T cells for the development of antibody-based T-cell therapy

Sci Rep..， 2019； 9(1)：13293

DOI:10.1038/s41598-019-49834-2

Maruta M, Ochi T, Tanimoto K, Asai H, Saitou T, Fujiwara H, Imamura T, Takenaka K, Yasukawa M.

Original paper Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment-colorectal cancer network

Sci Rep..， 2019； 9(1)：16378

DOI:10.1038/s41598-019-52816-z

Ieda T, Tazawa H, Okabayashi H, Yano S, Shigeyasu K, Kuroda S, Ohara T, Noma K, Kishimoto H, Nishizaki M, Kagawa S, Shirakawa Y, Saitou T, Imamura T, Fujiwara T.

Original paper Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro.

Sci Rep..， 2019； 9：17335

DOI:10.1038/s41598-019-53856-1

Nomura S, Takahashi H, Suzuki J, Kuwahara M, Yamashita M, Sawasaki T.

Original paper The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD.

J Biol Chem..， 2019； 294：14135-14148

DOI:10.1074/jbc.RA119.010119

Uematsu A, Kido K, Takahashi H, Takahashi C, Yanagihara Y, Saeki N, Yoshida S, Maekawa M, Honda M, Kai T, Shimizu K, Higashiyama S, Imai Y, Tokunaga F, Sawasaki T.

Original paper Histone H3K27 demethylase negatively controls the memory formation of antigen-stimulated CD8+ T cells.

J Immunol.， 2019； 202：1088-1098

DOI:10.4049/jimmunol.1801083

Yamada T, Nabe S, Toriyama K, Suzuki J, Inoue K, Imai Y, Shiraishi A, Takenaka K, Yasukawa M, Yamashita M

Original paper Safe childbirth for a type 1 antithrombin-deficient woman with novel mutation in the SERPINC1 gene undergoing antithrombin concentrate therapy.

Blood Coagul Fibrinolysis.， 2019； 30：47-51

DOI:10.1097/MBC.0000000000000785

Ikeda Y, Yamanouchi J, Hato T, Yasukawa M, Takenaka K

Original paper Direct comparison of target-reactivity and cross-reactivity induced by CAR- and BiTE-redirected T cells for the development of antibody-based T-cell therapy.

Sci Rep.， 2019； 9：13293

DOI:10.1038/s41598-019-49834-2

Maruta M, Ochi T, Tanimoto K, Asai H, Saitou T, Fujiwara H, Imamura T, Takenaka K, Yasukawa M.

Original paper Purification and Biochemical Characterization of Cysteine Protease from Baby Kiwi (Actinidia arguta).

Open Biochem. J..， 2019； 13：54-63

DOI:10.2174/1874091X01913010054

Miyazaki-Katamura S, Yoneta-Wada M, Kozuka M , Sakaue T, Yamane T, Suzuki J, Arakawa Y, Ohkubo I.

Original paper Recent Insights into Long Bone Development: Central Role of Hedgehog Signaling Pathway in Regulating Growth Plate

Int. J. Mol. Sci..， 2019； 20(23)：5840

DOI:10.3390/ijms20235840

Haraguchi R, Kitazawa R, Kohara Y, Ikedo A, Imai Y, Kitazawa S.

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