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Original paper Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways

mBio.， 2022； Jan 25;13(1）：e0370821

DOI:10.1128/mbio.03708-21

Sung-Jac Cha,Xiang Yu,Brian D Gregory,Yong Seok Lec,Tomoko Ishino,Robert O Opoka,Chandy C John,Marcelo Jacobs-Lorena

Original paper Novel animal model of soft tissue tumor due to aberrant hedgehog signaling activation in pericyte lineage

Cell Tissue Res..， 2022； 388：63-73

DOI:10.1007/s00441-022-03578-0

Haraguchi R, Kitazawa R, Kohara Y, Imai Y, Kitazawa S.

Original paper AGIA Tag System for Ultrastructural Protein Localization Analysis in Blood-Stage Plasmodium falciparum.

Front Cell Infect Microbiol..， 2021； 11：777291

DOI:10.3389/fcimb.2021.777291

Masayuki Morita, Bernard N. Kanoi, Naoaki Shinzawa, Rie Kubota, Hiroyuki Takeda, Tatsuya Sawasaki, Takafumi Tsuboi, Eizo Takashima

Original paper A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins

Biochem Pharmacol..， 2021； 194：114819

DOI:10.1016/j.bcp.2021.114819

Segawa R, Takeda H, Yokoyama T, Ishida M, Miyata C, Saito T, Ishihara R, Nakagita T, Sasano Y, Kanoh N, Iwabuchi Y, Mizuguchi M, Hiratsuka M, Hirasawa N.

Original paper Histone H3K27 demethylase, Utx, regulates osteoblast-to-osteocyte differentiation

Biochem Biophys Res Commun..， 2022； 590：132-138

DOI:10.1016/j.bbrc.2021.12.102

Xia Y, Ikedo A, Lee JW, Iimura T, Inoue K, Imai Y.

Original paper Macrophages are requisite for angiogenesis of type H vessels during bone regeneration in mice

Bone..， 2022； 154：116200

DOI:10.1016/j.bone.2021.116200

Kohara Y, Kitazawa R, Haraguchi R, Imai Y, Kitazawa S.

Original paper High-quality Fluorescence Imaging of the Human Acrosyringium Using a Transparency: Enhancing Technique and an Improved, Fluorescent Solvatochromic Pyrene Probe

Acta Histochem Cytochem..， 2020； 53(6)：131-138

DOI:10.1267/ahc.20-00020

Masamoto Murakami, Ryosuke Kawakami, Yosuke Niko, Teruko Tsuda, Hideki Mori, Kazuki Yatsuzuka, Takeshi Imamura, Koji Sayama

Original paper A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone

Bone Res.， 2021； 8(1)：41

DOI:10.1038/s41413-020-00115-z

Junichi Kushioka, Takashi Kaito, Rintaro Okada, Hiroyuki Ishiguro, Zeynep Bal, Joe Kodama, Ryota Chijimatsu, Melanie Pye, Masahiro Narimatsu, Jeffrey L. Wrana, Yasumichi Inoue, Hiroko Ninomiya, Shin Yamamoto, Takashi Saitou, Hideki Yoshikawa, Takeshi Imamura

Original paper Integrated Fluorescent Nanoprobe Design for High‐Speed In Vivo Two‐Photon Microscopic Imaging of Deep‐Brain Vasculature in Mice

Adv. Funct. Mater..， 2021； 31(20)：2010698

DOI:10.1002/adfm.202010698

Minami Takezaki, Ryosuke Kawakami, Shozo Onishi, Yasutaka Suzuki, Jun Kawamata, Takeshi Imamura, Shingo Hadano, Shigeru Watanabe, Yosuke Niko

Original paper New fluorescent three-dimensional and deep-imaging technique confirms a direct relationship between the acrosyringium and vesicles/pustules of palmoplantar pustulosis

J Dermatol Sci..， 2021； 102(2)：130-132

DOI:10.1016/j.jdermsci.2021.03.004

Masamoto Murakami, Ryosuke Kawakami, Yosuke Niko, Teruko Tsuda, Kazuki Yatsuzuka, Hideki Mori, Takeshi Imamura, Koji Sayama

Original paper Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy

Nat Commun.， 2021； 12(1)：5547

DOI:10.1038/s41467-021-25865-0

Kimiharu Takamatsu, Nobuyuki Tanaka, Kyohei Hakozaki, Ryohei Takahashi, Yu Teranishi, Tetsushi Murakami, Ryohei Kufukihara, Naoya Niwa, Shuji Mikami, Toshiaki Shinojima, Takashi Sasaki, Yusuke Sato, Haruki Kume, Seishi Ogawa, Kazuhiro Kakimi, Takashi Kamatani, Fuyuki Miya, Tatsuhiko Tsunoda, Eriko Aimono, Hiroshi Nishihara, Kazuaki Sawada, Takeshi Imamura, Ryuichi Mizuno, Mototsugu Oya

Original paper Wide Field Light-Sheet Microscopy with Lens-axicon Controlled Two-photon Bessel Beam Illumination

Nat Commun..， 2021； 12(1)：2979

DOI:10.1038/s41467-021-23249-y

Sota Takanezawa, Takashi Saitou, Takeshi Imamura

Original paper Donor–acceptor–acceptor-type near-infrared fluorophores that contain dithienophosphole oxide and boryl groups: Effect of the boryl group on the nonradiative decay

Chem Sci..， 2021； 12(18)：6333-6341

DOI:10.1039/D1SC00827G

Yoshiaki Sugihara, Naoto Inai, Thomas Baumgartner, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Masayasu Taki, Takeshi Yanai and Shigehiro Yamaguchi

Original paper Multiplexed single‑cell pathology reveals the association of CD8 T‑cell heterogeneity with prognostic outcomes in renal cell carcinoma

Cancer Immunol. Immunother..， 2021； 70：3001–3013

DOI:10.1007/s00262-021-03006-2

Tetsushi Murakami, Nobuyuki Tanaka, Kimiharu Takamatsu, Kyohei Hakozaki, Keishiro Fukumoto, Tsukasa Masuda, Shuji Mikami, Toshiaki Shinojima, Kazuhiro Kakimi, Tatsuhiko Tsunoda, Kazuaki Sawada, Takeshi Imamura, Ryuichi Mizuno, Mototsugu Oya

Original paper A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Nat Commun.， 2021； 12：430

DOI:10.1038/s41467-020-20658-3

3. Iriguchi S, Yasui Y, Kawai Y, Arima S, Kunitomo M, Sato T, Ueda T, Minagawa A, Mishima Y, Yanagawa N, Baba Y, Miyake Y, Nakayama K, Takiguchi M, Shinohara T, Nakatsura T, Yasukawa M, Kassai Y, Hayashi A, Kaneko S

Original paper A multicenter non-randomized, uncontrolled single arm trial for evaluation of the efficacy and the safety of the treatment with favipiravir for patients with severe fever with thrombocytopenia syndrome.

PLoS Negl Trop Dis.， 2021； 15：e0009103

DOI:10.1371/journal.pntd.0009103

2. Suemori K, Saijo M, Yamanaka A, Himeji D, Kawamura M, Haku T, Hidaka M, Kamikokuryo C, Kakihana Y, Azuma T, Takenaka K, Takahashi T, Furumoto A, Ishimaru T, Ishida M, Kaneko M, Kadowaki N, Ikeda K, Sakabe S, Taniguchi T, Ohge H, Kurosu T, Yoshikawa T, Shimojima M, Yasukawa M.

Original paper Malaria Parasite Species Composition of Plasmodium Infections Among Asymptomatic and Symptomatic School-Age Children in Rural and Urban Areas of Kinshasa, Democratic Republic of Congo

Malaria Journal.， 2021； 20：389

DOI:10.1186/s12936-021-03919-4

Sabin S Nundu , Richard Culleton, Shirley V Simpson, Hiroaki Arima , Jean-Jacques Muyembe, Toshihiro Mita , Steve Ahuka , Taro Yamamoto

Original paper High incidence of asymptomatic cases during an outbreak of Plasmodium malariae in a remote village of Malaysian Borneo

PLoS Neglected Tropical Diseases.， 2021； 15(6)：e0009450

DOI:10.1371/journal.pntd.0009450

Nurul Athirah Naserrudin, Emira Izzati Abdul Aziz, Erdie Aljet, George Mangunji, Bumpei Tojo, Mohammad Saffree Jeffree, Richard Culleton, Kamruddin Ahmed

Original paper High prevalence of Plasmodium malariae and Plasmodium ovale in co-infections with Plasmodium falciparum in asymptomatic malaria parasite carriers in Southwest Nigeria

International Journal For Parasitology.， 2021； 11：S0020-7519 (21) 00239-3

DOI:10.1016/j.ijpara.2021.06.003

Muhydeen Abiodun Abdulraheem, Medard Ernest, Ifeoma Ugwuanyi, Hussein M Abkallo, Saori Nishikawa, Mofeyisade Adeleke, Adebola E Orimadegun, Richard Culleton

Original paper Prevalence of Plasmodium falciparum Isolates Lacking the Histidine Rich Protein 2 Gene Among Symptomatic Malaria Patients in Kwilu Province, DR. Congo

Infectious Diseases of Poverty.， 2021； 10：77

DOI:10.1186/s40249-021-00860-1

Yannick Bazitama Munyeku, Alain Abera Musaka, Medard Ernest, Chris Smith, Paul Mankadi Mansiangi, Richard Culleton