To the Future with
PROTEO-SCIENCE

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ABOUT PROS

Proteins are the building blocks of life. The wheat cell-free protein synthesis method, pioneered here at PROS, enables the high-throughput, large scale synthesis of high quality proteins.

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PRiME

PRiME is a joint-use, collaborative research center focusing on interactome analysis set up by the Proteo-Science Center at Ehime University.
Collaborative research is the bedrock of our center, and we are continuously adapting our program to facilitate our ability to work together with researchers all over the world.

DEPARTMENTS

The Proteo-Science Center at Ehime University consists of various diverse research departments affiliated with 'Fundamental Technology Development‘ and 'Complex Bioscience Analysis’. We aim to promote protein-based life science research, and to use our expertise to inform the development of novel diagnostics and therapeutics for the improvement of human health.

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ACHIEVEMENTS

Original paper Long-term Nlrp3 gain-of-function mutation promotes cardiac dysfunction independent of inflammasome in mice

The Journal of Immunology., 2026; 215(10):vkag257
DOI:10.1093/jimmun/vkag257
Mie Kurata , Kayo Takahashi , Naoe Kaneko , Kenji Kameda , Takanori Nakamura , Sho Hosokawa , Kasumi Murakami , Hideki Ogura , Satoshi Ishido , Osamu Yamaguchi , Junya Masumoto

Original paper Structural and functional analysis of a photosystem II mutant PsbA3-S264V

Biochim. Biophys. Acta (Bioenergetics)., 2026; 1867:149607
DOI:10.1016/j.bbabio.2026.149607
Songbo, F., Nakajima, Y., Kato, K., Jiang. H., Tsai, P.-C-, Jia A., Sugiura, M. and Shen, J.R.

Original paper Cryo-EM structure of photosystem II D1-V185T mutant from Thermosynechococcus vestitus

Biochim. Biophys. Acta (Bioenergetics)., 2026; 1867:149598
DOI:10.1016/j.bbabio.2026.149598
Jiang, H., Nakajima, Y., Akita, F., Li, H., Kato, K., Sugiura, M., and Shen, J.-R.

Original paper Stage-specific expression and localization of ETRAMP4 during gametocyte development in the malaria parasite Plasmodium falciparum

Parasitology International., 2026; 117:103390
DOI:10.1016/j.parint.2026.103390
H Iriko, A Omoda, H Aoi, M Tachibana, T Ishino, H Otsuki, T Tsuboi

Original paper Theophylline-dependent synthetic riboswitches enable tightly regulated inducible gene expression in tobacco plastids

Plant Biotechnol.., 2026; 43:333-341
DOI:10.5511/plantbiotechnology.26.0622a
Rika Yamane, Atsushi Ogawa, Takashi Shiina, Yuzuru Tozawa, Yoichi Nakahira