ACHIEVEMENTS 研究業績

SEARCH ACHIEVEMENTS

検索条件を入力、または選択をして、SEARCHボタンを押してください

英文原著 CDH11 contributes to bladder cancer progression via regulation of mitochondrial energy metabolism

Cancer Med..， 2025； 14(22)：e71399

DOI:10.1002/cam4.71399

Arai O, Yanagihara Y, Arai H, Watanabe R, Miura N, Kikugawa T, Saika T, Imai Y.

英文原著 Estrogen signaling in PDGFRα+ cells positively regulates cortical bone metabolism via IGFBP5 in female mice

JBMR Plus..， 2025； 1：ziaf178

DOI:10.1093/jbmrpl/ziaf178

Ikedo A, Aoki R, Sakai H, Saeki N, Yanagihara Y, Moody J, Kojima M, Kouno T, Ando Y, Hino K, Kinoshita T, Carninci P, Shin JW, Hon CC, Uezumi A, Kamei Y, Imai Y.

英文原著 Claudin 5-binding small molecule transiently opens the blood-brain barrier and safely enhances brain drug delivery

J Control Release.， 2025； 388：114314

DOI:10.1016/j.jconrel.2025.114314

Saito Inoue, Keisuke Shirakura, Atsuya Shirono, Jumpei Taguchi, Yoshiki Ikeda, Satomi Tomita, Risa Funatsu, Kosuke Muraoka, Yosuke Hashimoto, Keisuke Tachibana, Nobumasa Hino, Takefumi Doi, Yui Ikemi, Kazuto Nunomura, Bangzhong Lin, Shinsaku Nakagawa, Kazutake Tsujikawa, Shota Tanaka, Masanori Obana, Yasushi Fujio, Takamitsu Hosoya, Hiroyuki Takeda, Masuo Kondoh, Yoshiaki Okada

英文原著 Size-selective permeation-enhancing modulation of the tight junction by receptor-binding domains of Clostridium perfringens enterotoxin and Clostridium perfringens iota-toxin

Tissue Barriers.， 2025； 13：2459963

DOI:10.1080/21688370.2025.2459963

Keisuke Tachibana, Sayaka Sugimura, Shuko Sakimura, Lin Bai, Hiroshi Aoyama, Hiroyuki Takeda, Yuki Niwa, Masahiro Nagahama, Masuo Kondoh

英文原著 Structural basis of the hepatitis B virus X protein in complex with DDB1

Proc Natl Acad Sci U S A.， 2025； 122：e2421325122

DOI:10.1073/pnas.2421325122

Hiroki Tanaka, Joao Diogo Dias, Basile Jay, Shunsuke Kita, Mina Sasaki, Hiroyuki Takeda, Naoki Kishimoto, Shunsuke Sasaki, Shogo Misumi 5, Masashi Mizokami, Christine Neuveut, Takashi Sumikama, Mikihiro Shibata, Katsumi Maenaka, Shinichi Machida

英文原著 Caspase-mediated cleavage of a scaffold protein, MPRIP, yields a truncated form that is involved in repetitive bleb formation

FEBS Journal.， 2025； 292：2287-2305

DOI:10.1111/febs.17422

Kazuhiro Sakamaki, Naohisa Sakamoto, Yuki Tsujimura, Takahiro Iwasaki, Takuma Kawamura, Jun Nakabayashi, Rhea S. D'Souza, Arooma Jannat, Ken-ichiro Takeshima, Hiroyuki Takeda, Koji Koyamada, Hideo Yokota

英文原著 Machine learning-based insights into circulating autoantibody dynamics and treatment outcomes in patients with NSCLC receiving immune checkpoint inhibitors.

Front Immunol..， 2025； 16：1666030

DOI:10.3389/fimmu.2025.1666030.

Wei F, Takeda H, Azuma K, Nakahara Y, Igarashi Y, Murotani K, Saito H, Murakami S, Kondo T, Kouro T, Himuro H, Tsuji K, Komahashi M, Sawasaki T, Sasada T.

英文原著 In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID.

Commun Biol..， 2025； 8：1323

DOI:10.1038/s42003-025-08761-x.

Yamada K, Yamanaka S, Yamakoshi H, Kohyama A, Iwabuchi Y, Kosako H, Sawasaki T.

英文原著 ZFP36L1 and L2 as novel antiviral factors for Crimean-Congo hemorrhagic fever virus via interaction with viral nucleoprotein.

J Biol Chem..， 2025； 301：110545

DOI:10.1016/j.jbc.2025.110545.

Hirano M, Nochi K, Matsugi M, Furukawa C, Takeda H, Sakurai Y, Kurosaki Y, Sawasaki T, Yasuda J, Takahashi H, Yoshii K.

英文原著 Structural insights into CDF1 accumulation on the CONSTANS promoter via a plant-specific DNA-binding domain.

Nat Plants..， 2025； 11：836-848

DOI:10.1038/s41477-025-01946-6.

Furihata H, Zhu Z, Nishida K, Sakuraba Y, Tsuji A, Yamashita H, Nosaki S, Tachibana R, Yamagami A, Ikeda Y, Abe M, Sawasaki T, Nakano T, Yanagisawa S, Tanokura M, Miyakawa T.

英文原著 Amino acid-dependent TSC2 dephosphorylation by lysosome-PP2A regulates mTORC1 signaling transduction.

Life Sci Alliance..， 2025； 8：e202503206

DOI:10.26508/lsa.202503206.

Nakamura T, Nada S, Matsumoto M, Loling Othman N, Kosako H, Ikeda K, Koshikawa N, Masumoto J, Sawasaki T, Takekawa M, Suzuki T, Okada M.

英文原著 Retrieval from vacuolar and endosomal compartments underpinning the neofunctionalization of SNARE in plants.

Nat Plants..， 2025； 11：2168–2180

DOI:10.1038/s41477-025-02115-5.

Feng Y, Ebine K, Ito Y, Kanazawa T, Sawasaki T, Nozawa A, Uemura T, Nakano A, Ueda T.

英文原著 Histone Modification-Dependent Transcriptional Regulation of Defence Genes in Early Response of Arabidopsis to Spodoptera litura Attack.

Plant Cell Environ..， 2025； 48：3257-3268

DOI:10.1111/pce.15345.

Yusuf A, Wakaya K, Sakamoto T, Uemura T, Okamura K, Ramadan A, Nozawa A, Suzuki T, Inui Y, Matsunaga S, Sawasaki T, Arimura GI.

英文原著 Discovery of Evolutionary Loss of the Ubiquitin-like Autophagy-Related ATG12 System in a Lineage of Apicomplexa.

Cells.， 2025； 14：121

DOI:10.3390/cells14020121

Lin XX, Bai YD, Wang ST, Nozawa A, Sawasaki T, Masatani T, Hikosaka K, Asada M, Sakamoto H.

英文原著 Vesicles Secreted by Renal Cell Carcinoma Cells Cause Vascular Endothelial Cells to Express PSMA and Drive Tumor Progression

Cells.， 2025； 22;14(3)：165

DOI:10.3390/cells14030165

Ryuta Watanabe, Keito Kagimoto, Mami Chosei, Tomohisa Sakaue, Mie Kurata, Noriyoshi Miura, Riko Kitazawa, Tadahiko Kikugawa, Shigeki Higashiyama, Takashi Saika

英文原著 Reliable intraoperative diagnostic methods for PCNSL: utility of combining intraoperative immunohistochemistry, cytology, and flow cytometry in achieving optimal treatment

Acta Neurol Belg.， 2025； 125(1)：99-108

DOI:10.1007/s13760-024-02637-3

Akihiro Inoue, Yukihiro Miyazaki, Hideaki Watanabe, Masahiro Nishikawa, Kosuke Kusakabe, Takanori Ohnishi, Mashio Taniwaki, Takatsugu Honda, Takuya Kondo, Shingo Kinnami, Eiji Katayama, Seiji Shigekawa, Mie Kurata, Riko Kitazawa, Takeharu Kunieda

英文原著 Artificial intelligence challenge of discriminating cutaneous arteritis and polyarteritis nodosa based on hematoxylin-and-eosin images of skin biopsy specimens

Pathol Res Pract.， 2025； 269：155915

DOI:10.1016/j.prp.2025.155915

Wataru Kashiwa, Kenji Hirata, Hiroki Endo, Kohsuke Kudo, Chietsugu Katoh, Tamihiro Kawakami, Hiroyuki Kanno, Kei Takahashi, Tatsuhiko Miyazaki, Eiji Ikeda, Toshiaki Oharaseki, Yayoi Ogawa, Mitsuho Onimaru, Mie Kurata, Daigo Nakazawa, Eri Muso, Yuka Nishibata, Sakiko Masuda, Utano Tomaru, Yoshihiro Matsuno, Shunsuke Furuta, Yoshiyuki Abe, Naoto Tamura, Masayoshi Harigai, Akihiro Ishizu

英文原著 Usefulness of four-dimensional noise reduction filtering using a similarity algorithm in low-dose dynamic computed tomography for the evaluation of breast cancer: a preliminary study

Japanese journal of radiology.， 2025； May;43(5)：787-799

DOI:10.1007/s11604-024-01730-0

Daichi Uraoka, Megumi Matsuda, Yuki Tanabe, Naoto Kawaguchi, Chihiro Nishiyama, Ayaka Okada, Koichiro Uda, Hiroshi Suekuni, Hikaru Nishiyama, Yoshiaki Kamei, Mie Kurata, Riko Kitazawa, Shota Nakano, Teruhito Kido

英文原著 Diagnostic accuracy of a machine learning model using radiomics features from breast synthetic MRI.

BMC Medical Imaging.， 2025； 2025 Sep 29;25(1)：399

DOI:10.1186/s12880-025-01930-8

Takuya Matsuda, Megumi Matsuda, Hasnine Haque, Shotaro Fuchibe, Masaki Matsumoto, Yasuhiro Shiraishi, Yuki Nobe, Kango Kuwabara, Wataru Toshimori, Kanako Okada, Naoto Kawaguchi, Mie Kurata, Yoshiaki Kamei, Riko Kitazawa, Teruhito Kido

英文原著 Co-expression of CD30 and SLFN11 serves as a dual biomarker for the treatment of cutaneous T-cell lymphoma

NAR Cancer..， 2025； 7(4)：zcaf037

DOI:https://doi.org/10.1093/narcan/zcaf037

Takatoshi Shimauchi, Junko Murai, Manami Iwasaki, Pawit Phadungsaksawasdi, Toshiyuki Ojima, Kazuyasu Fujii, Tetsuya Honda