Achievements

Original paper ScreenCap3: Improving prediction of caspase-3 cleavage sites using experimentally verified noncleavage sites.

Proteomics.， 2014； 14：2042-2046

DOI:10.1002/pmic.201400002

Fu SC, Imai K, Sawasaki T, Tomii K.

Original paper Identification of RFPL3 protein as a novel E3 ubiquitin ligase modulating the integration activity of human immunodeficiency virus, type 1 preintegration complex using a microtiter plate-based assay.

J Biol Chem..， 2014； 289：26368-26382

DOI:10.1074/jbc.M114.561662

Tan BH, Suzuki Y, Takahashi H, Ying PH, Takahashi C, Han Q, Chin WX, Chao SH, Sawasaki T, Yamamoto N, Suzuki Y.

Original paper The Apoptotic Initiator Caspase-8: Its Functional Ubiquity and Genetic Diversity during Animal Evolution.

Mol Biol Evol..， 2014； 31：3282-3301

DOI:10.1093/molbev/msu260

Sakamaki K, Shimizu K, Iwata H, Imai K, Satou Y, Funayama N, Nozaki M, Yajima M, Nishimura O, Higuchi M, Chiba K, Yoshimoto M, Kimura H, Gracey AY, Shimizu T, Tomii K, Gotoh O, Akasaka K, Sawasaki T, Miller DJ.

Original paper Overexpression of the PAP1 transcription factor reveals a complex regulation of flavonoid and phenylpropanoid metabolism in Nicotiana tabacum plants attacked by Spodoptera litura.

PLoS One.， 2014； 9：e108849

DOI:10.1371/journal.pone.0108849

Mitsunami T, Nishihara M, Galis I, Alamgir KM, Hojo Y, Fujita K, Sasaki N, Nemoto K, Sawasaki T, Arimura G.

Original paper The ligand binding ability of dopamine D1 receptors synthesized using a wheat germ cell-free protein synthesis system with liposomes.

Eur J Pharmacol..， 2014； 745：117-122

DOI:10.1016/j.ejphar.2014.10.011

Arimitsu E, Ogasawara T, Takeda H, Sawasaki T, Ikeda Y, Hiasa Y, Maeyama K.

Original paper Identification of novel transcription factors in osteoclast differentiation using genome-wide analysis of open chromatin determined by DNase-seq.

J Bone Miner Res.， 2014； 29(8)：1823-32

DOI:10.1002/jbmr.2229

Inoue K, Imai Y.

Original paper Genome-wide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis.

J Bone Miner Res.， 2014；：

DOI:10.1002/jbmr.2418

Omata Y, Yasui T, Hirose J, Izawa N, Imai Y, Matsumoto T, Masuda H, Tokuyama N, Nakamura S, Tsutsumi S, Yasuda H, Okamoto K, Takayanagi H, Hikita A, Imamura T, Matsuo K, Saito T, Kadono Y, Aburatani H, Tanaka S.

Original paper Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.

FEBS Lett.， 2014； 588(14)：132463

DOI:10.1016/j.febslet.2014.05.009

Enoki Y, Sato T, Tanaka S, Iwata T, Usui M, Takeda S, Kokabu S, Matsumoto M, Okubo M, Nakashima K, Yamato M, Okano T, Fukuda T, Chida D, Imai Y, Yasuda H, Nishihara T, Akita M, Oda H, Okazaki Y, Suda T, Yoda T.

Original paper Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo.

Biochem Biophys Res Commun.， 2014； 450(1)：416-22

DOI:10.1016/j.bbrc.2014.05.114

Yu TY, Kondo T, Matsumoto T, Fujii-Kuriyama Y, Imai Y.

Original paper Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle.

Endocrinology.， 2014； 155(7)：2467-79

DOI:10.1210/en.2014-1008

Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P, Yamada G.

Original paper Novel type of adenylyl cyclase participates in tabtoxinine-β-lactam-induced cell death and occurrence of wildfire disease in Nicotiana benthamiana.

Plant Signal Behav..， 2014； 9：e27420

DOI:10.4161/psb.27420

Ito M, Takahashi H, Sawasaki T, Ohnishi K, Hikichi Y, Kiba A.

Original paper Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

PLoS Genet.， 2014； 10(5)：e1004386

DOI:10.1371/journal.pgen.1004386

Sakakibara I, Santolini M, Ferry A, Hakim V, Maire P.

Original paper Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice.

Bone.， 2014； 60：68-77

DOI:10.1016/j.bone.2013.12.005

Kondoh S, Inoue K, Igarashi K, Sugizaki H, Shirode-Fukuda Y, Inoue E, Yu T, Takeuchi J, Kanno J, Bonewald L, Imai Y.

Original paper Live imaging-based model selection reveals periodic regulation of the stochastic g1/s phase transition in vertebrate axial development.

PLoS Comput Biol..， 2014； 10：e1003957

DOI:10.1371/journal.pcbi.1003957

Sugiyama M, Saitou T, Kurokawa H, Sakaue-Sawano A, Imamura T, Miyawaki A, Iimura T.

Original paper Functional heterogeneity of osteocytes in FGF23 production: the possible involvement of DMP1 as a direct negative regulator.

Bonekey Rep..， 2014； 3：543

DOI:10.1038/bonekey

Lee JW, Yamaguchi A, Iimura T.

Original paper Roles of raft-anchored adaptor Cbp/PAG1 in spatial regulation of c-Src kinase.

PLoS One.， 2014； 9：e93470

DOI:10.1371/journal.pone.0093470

Saitou T, Kajiwara K, Oneyama C, Suzuki T, Okada M.

Original paper Intravital multiphoton fluorescence imaging and optical manipulation of spinal cord in mice, using a compact fiber laser system.

Lasers Surg Med..， 2014； 46：563-72

DOI:10.1002/lsm.22266

Oshima Y, Horiuch H, Honkura N, Hikita A, Ogata T, Miura H, Imamura T.

Original paper In vivo subcellular imaging of tumors in mouse models using a fluorophore-conjugated anti-carcinoembryonic antigen antibody in two-photon excitation microscopy.

Cancer Sci..， 2014； 105：1299-306

DOI:10.1111/cas.12500

Koga S, Oshima Y, Honkura N, Iimura T, Kameda K, Sato K, Yoshida M, Yamamoto Y, Watanabe Y, Hikita A, Imamura T.

Original paper Tricomponent complex loaded with a mosquito-stage antigen of the malaria parasite induces potent transmission-blocking immunity

Clin Vaccine Immunol.， 2014； 21：561-569

DOI:10.1128/CVI.00053-14

Arakawa T, Tsuboi T, Sattabongkot J, Sakao K, Torii M, Miyata T

Original paper Characteristic age distribution of Plasmodium vivax infections after malaria elimination on Aneityum Island, Vanuatu

Infect Immun.， 2014； 82：243-252

DOI:10.1128/IAI.00931-13

Kaneko A, Chaves LF, Taleo G, Kalkoa M, Isozumi R, Wickremasinghe R, Perlmann H, Takeo S, Tsuboi T, Tachibana S, Kimura M, Björkman A, Troye-Blomberg M, Tanabe K, Drakeley C

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