Achievements

Original paper Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria

Cell Host Microbe.， 2014； 15：551-563

DOI:10.1016/j.chom.2014.04.008

Hong Zhao, Taiki Aoshi, Satoru Kawai, Yuki Mori, Aki Konishi, Muge Ozkan, Yukiko Fujita, Yasunari Haseda, Mikiko Shimizu, Masako Kohyama, Kouji Kobiyama, Kei Eto, Junichi Nabekura, Toshihiro Horii, Tomoko Ishino, Masao Yuda, Hiroaki Hemmi, Tsuneyasu Kaisho, Shizuo Akira, Manabu Kinoshita, Koujiro Tohyama, Yoshichika Yoshioka, Ken J. Ishii, Cevayir Coban,

Original paper D-Glucose concentration is the key factor facilitating liver stage maturation of Plasmodium

Parasitol Int.， 2014； 63：584-590

DOI:10.1016/j.parint.2014.03.004

Satoko Itani, Motomi Torii, Tomoko Ishino

Original paper The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions.

Retrovirology.， 2014； 11：9

DOI:10.1186/1742-4690-11-9

Kudoh A, Takahama S, Sawasaki T, Ode H, Yokoyama M, Okayama A, Ishikawa A, Miyakawa K, Matsunaga S, Kimura H, Sugiura W, Sato H, Hirano H, Ohno S, Yamamoto N, Ryo A.

Original paper Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.

Genes Cells.， 2014； 19：254-272

DOI:10.1111/gtc.12128

Takiuchi T, Nakagawa T, Tamiya H, Fujita H, Sasaki Y, Saeki Y, Takeda H, Sawasaki T, Buchberger A, Kimura T, Iwai K.

Original paper In situ visualization of plasma cells producing antibodies reactive to Porphyromonas gingivalis in periodontitis: the application of the enzyme-labeled antigen method.

Mol Oral Microbiol..， 2014； 29：156-173

DOI:10.1111/omi.12052

Mizutani Y, Tsuge S, Takeda H, Hasegawa Y, Shiogama K, Onouchi T, Inada K, Sawasaki T, Tsutsumi Y.

Original paper Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.

J Virol..， 2014； 88：7541-7555

DOI:10.1128/JVI.03170-13

Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T.

Original paper ScreenCap3: Improving prediction of caspase-3 cleavage sites using experimentally verified noncleavage sites.

Proteomics.， 2014； 14：2042-2046

DOI:10.1002/pmic.201400002

Fu SC, Imai K, Sawasaki T, Tomii K.

Original paper Identification of RFPL3 protein as a novel E3 ubiquitin ligase modulating the integration activity of human immunodeficiency virus, type 1 preintegration complex using a microtiter plate-based assay.

J Biol Chem..， 2014； 289：26368-26382

DOI:10.1074/jbc.M114.561662

Tan BH, Suzuki Y, Takahashi H, Ying PH, Takahashi C, Han Q, Chin WX, Chao SH, Sawasaki T, Yamamoto N, Suzuki Y.

Original paper The Apoptotic Initiator Caspase-8: Its Functional Ubiquity and Genetic Diversity during Animal Evolution.

Mol Biol Evol..， 2014； 31：3282-3301

DOI:10.1093/molbev/msu260

Sakamaki K, Shimizu K, Iwata H, Imai K, Satou Y, Funayama N, Nozaki M, Yajima M, Nishimura O, Higuchi M, Chiba K, Yoshimoto M, Kimura H, Gracey AY, Shimizu T, Tomii K, Gotoh O, Akasaka K, Sawasaki T, Miller DJ.

Original paper Overexpression of the PAP1 transcription factor reveals a complex regulation of flavonoid and phenylpropanoid metabolism in Nicotiana tabacum plants attacked by Spodoptera litura.

PLoS One.， 2014； 9：e108849

DOI:10.1371/journal.pone.0108849

Mitsunami T, Nishihara M, Galis I, Alamgir KM, Hojo Y, Fujita K, Sasaki N, Nemoto K, Sawasaki T, Arimura G.

Original paper The ligand binding ability of dopamine D1 receptors synthesized using a wheat germ cell-free protein synthesis system with liposomes.

Eur J Pharmacol..， 2014； 745：117-122

DOI:10.1016/j.ejphar.2014.10.011

Arimitsu E, Ogasawara T, Takeda H, Sawasaki T, Ikeda Y, Hiasa Y, Maeyama K.

Original paper Identification of novel transcription factors in osteoclast differentiation using genome-wide analysis of open chromatin determined by DNase-seq.

J Bone Miner Res.， 2014； 29(8)：1823-32

DOI:10.1002/jbmr.2229

Inoue K, Imai Y.

Original paper Genome-wide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis.

J Bone Miner Res.， 2014；：

DOI:10.1002/jbmr.2418

Omata Y, Yasui T, Hirose J, Izawa N, Imai Y, Matsumoto T, Masuda H, Tokuyama N, Nakamura S, Tsutsumi S, Yasuda H, Okamoto K, Takayanagi H, Hikita A, Imamura T, Matsuo K, Saito T, Kadono Y, Aburatani H, Tanaka S.

Original paper Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.

FEBS Lett.， 2014； 588(14)：132463

DOI:10.1016/j.febslet.2014.05.009

Enoki Y, Sato T, Tanaka S, Iwata T, Usui M, Takeda S, Kokabu S, Matsumoto M, Okubo M, Nakashima K, Yamato M, Okano T, Fukuda T, Chida D, Imai Y, Yasuda H, Nishihara T, Akita M, Oda H, Okazaki Y, Suda T, Yoda T.

Original paper Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo.

Biochem Biophys Res Commun.， 2014； 450(1)：416-22

DOI:10.1016/j.bbrc.2014.05.114

Yu TY, Kondo T, Matsumoto T, Fujii-Kuriyama Y, Imai Y.

Original paper Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle.

Endocrinology.， 2014； 155(7)：2467-79

DOI:10.1210/en.2014-1008

Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P, Yamada G.

Original paper Novel type of adenylyl cyclase participates in tabtoxinine-β-lactam-induced cell death and occurrence of wildfire disease in Nicotiana benthamiana.

Plant Signal Behav..， 2014； 9：e27420

DOI:10.4161/psb.27420

Ito M, Takahashi H, Sawasaki T, Ohnishi K, Hikichi Y, Kiba A.

Original paper Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

PLoS Genet.， 2014； 10(5)：e1004386

DOI:10.1371/journal.pgen.1004386

Sakakibara I, Santolini M, Ferry A, Hakim V, Maire P.

Original paper Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice.

Bone.， 2014； 60：68-77

DOI:10.1016/j.bone.2013.12.005

Kondoh S, Inoue K, Igarashi K, Sugizaki H, Shirode-Fukuda Y, Inoue E, Yu T, Takeuchi J, Kanno J, Bonewald L, Imai Y.

Original paper Live imaging-based model selection reveals periodic regulation of the stochastic g1/s phase transition in vertebrate axial development.

PLoS Comput Biol..， 2014； 10：e1003957

DOI:10.1371/journal.pcbi.1003957

Sugiyama M, Saitou T, Kurokawa H, Sakaue-Sawano A, Imamura T, Miyawaki A, Iimura T.

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