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Original paper Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Nat Commun..， 2016； 7：12547
DOI:10.1038/ncomms12547
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F.

Original paper AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody against Human Dopamine Receptor D1 for Protein Analysis.

PLoS One..， 2016； 11：e0156716
DOI:10.1371/journal.pone.0156716
Yano T, Takeda H, Uematsu A, Yamanaka S, Nomura S, Nemoto K, Iwasaki T, Takahashi H, Sawasaki T.

Original paper Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins.

PLoS One..， 2016； 11：e0156718
DOI:10.1371/journal.pone.0156718
Takahashi H, Uematsu A, Yamanaka S, Imamura M, Nakajima T, Doi K, Yasuoka S, Takahashi C, Takeda H, Sawasaki T.

Original paper Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication.

PLoS Pathog..， 2016； 12：e1005357
DOI:10.1371/journal.ppat.1005357
Suzuki Y, Chin WX, Han Q, Ichiyama K, Lee CH, Eyo ZW, Ebina H, Takahashi H, Takahashi C, Tan BH, Hishiki T, Ohba K, Matsuyama T, Koyanagi Y, Tan YJ, Sawasaki T, Chu JJ, Vasudevan SG, Sano K, Yamamoto N.

Original paper Involvement of the 3’ Untranslated Region in Encapsidation of the Hepatitis C Virus.

PLoS Pathog..， 2016； 12：e1005441
DOI:10.1371/journal.ppat.1005441
Shi G, Ando T, Suzuki R, Matsuda M, Nakashima K, Ito M, Omatsu T, Oba M, Ochiai H, Kato T, Mizutani T, Sawasaki T, Wakita T, Suzuki T.

Original paper H11/HSPB8 Restricts HIV-2 Vpx to Restore the Anti-Viral Activity of SAMHD1.

Front Microbiol..， 2016； 7：883
DOI:10.3389/fmicb.2016.00883
Kudoh A, Miyakawa K, Matsunaga S, Matsushima Y, Kosugi I, Kimura H, Hayakawa S, Sawasaki T, Ryo A.

Original paper Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage.

Biochim Biophys Acta..， 2016； S0167-4889：30215-4
DOI:10.1016/j.bbamcr.2016.08.010
Sakamaki K, Ishii TM, Sakata T, Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Jung SK, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N.

Original paper Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.

Immunology.， 2016； 147：476-87
DOI:10.1111/imm.12580
Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M.

Original paper Identification of Nedd9 as a TGF-β-Smad2/3 Taget Gene Involved in RANKL-Induced Osteoclastgenesis by Comprehensive Analysis

PLoS One..， 2016； 11(6)：e0157992
DOI:10.1371/journal.pone.0157992
Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, Matsumoto T, Imai Y, Seo S, Kurokawa M, Tsutsumi S, Kadono Y, Morimoto C, Aburatani H, Miyamoto T, Tanaka S.

Original paper MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis.

Nucleic Acids Res..， 2016； ：
DOI:10.1093/nar/gkw512
Santolini M, Sakakibara I, Gauthier M, Ribas-Aulinas F, Takahashi H, Sawasaki T, Mouly V, Concordet JP, Defossez PA, Hakim V, Maire P.

Original paper High-throughput production of a stable isotope-labeled peptide library for targeted proteomics using a wheat germ cell-free synthesis system

Mol. BioSyst..， 2016； 12(8)：2389-2393
DOI:10.1039/c6mb00209a
Takemori N, Takemori A, Tanaka Y, Ishizaki J, Hasegawa H, Shiraishi A, Ohashi Y.

Original paper MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis.

Nucleic Acids Res..， 2016； 44(18)：8621-8640
DOI:10.1093/nar/gkw512
Santolini M, Sakakibara I, Gauthier M, Ribas-Aulinas F, Takahashi H, Sawasaki T, Mouly V, Concordet JP, Defossez PA, Hakim V, Maire P.

Original paper Biofunction-assisted DNA detection through RNase H-enhanced 3’ processing of a premature tRNA probe in a wheat germ extract

Bioorg. Med. Chem. Lett..， 2016； 26：3658-3661
DOI:10.1016/j.bmcl.2016.05.091
Ogawa A, Tabuchi J, Doi Y, Takamatsu M

Original paper sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss.

Sci Rep.， 2016； 6：25198
DOI:10.1038/srep25198
Haraguchi R, Kitazawa R, Mori K, Tachibana R, Kiyonari H, Imai Y, Abe T, Kitazawa S.

Original paper Two clonal types of human skin fibroblasts with different potentials for proliferation and tissue remodeling ability.

J Dermatol Sci..， 2016； 16：S0923-1811
DOI:10.1016/j.jdermsci.2016.01.009
Hiraoka C, Toki F, Shiraishi K, Sayama K, Nishimura EK, Miura H, Higashiyama S, Nanba D.

Original paper Rational optimization of amber suppressor tRNAs toward efficient incorporation of a non-natural amino acid into protein in a eukaryotic wheat germ extract

Org. Biomol. Chem..， 2016； 14：2671-2678
DOI:10.1039/C5OB02533H
Ogawa A, Namba Y, Gakumasawa M

Original paper Quantitative SHG imaging in osteoarthritis model mice implying a diagnostic application

Biomedical Optics Express.， 2015； 6：405-420
DOI:10.1364/BOE.6.000405
Hiroshi Kiyomatsu, Yusuke Oshima, Takashi Saitou, Tsuyoshi Miyazaki, Atsuhiko Hikita, Hiromasa Miura, Tadahiro Iimura, Takeshi Imamura

Original paper Arkadia enhances BMP signaling through ubiquitylation and degradation of Smad6

The Journal of Biochemistry.， 2015； 158：61-71
DOI:10.1093/jb/mvv024
Yutaro Tsubakihara, Atsuhiko Hikita, Shin Yamamoto, Sachi Matsushita, Natsuki Matsushita, Yusuke Oshima, Keiji Miyazawa and Takeshi Imamura

Original paper Evaluation of Injured Axons Using Two-Photon Excited Fluorescence Microscopy after Spinal Cord Contusion Injury in YFP-H Line Mice

International Journal of Molecular Sciences.， 2015； 16：15785-99
DOI:10.3390/ijms160715785
Hideki Horiuchi, Yusuke Oshima, Tadanori Ogata, Tadao Morino, Seiji Matsuda, Hiromasa Miura and Takeshi Imamura

Original paper Analyses of bone modeling and remodeling using in vitro reconstitution system with two-photon microscopy

Bone.， 2015； 76：44698
DOI:10.1016/j.bone.2015.02.030
Atsuhiko Hikita, Tadahiro Iimura, Yusuke Oshima, Takashi Saitou, Shin Yamamoto and Takeshi Imamura
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