Achievements

Original paper Oral mucosal fibroblasts overexpressing BMP-2 differentiate into osteoblasts and participate in new bone formation during bone regeneration.

Journal of Oral Biosciences.， 2015； 57：118–123

DOI:10.1016/j.job.2015.01.001

Lin Z, Iimura T, Kasugai S, Yamaguchi A.

Original paper Changes in the spatial distribution of sclerostin in the osteocytic lacuno-canalicular system in alveolar bone due to orthodontic forces, as detected on multimodal confocal fluorescence imaging analyses.

Arch Oral Biol..， 2015； 60：45-54

DOI:10.1016/j.archoralbio

Nishiyama Y, Matsumoto T, Lee JW, Saitou T, Imamura T, Moriyama K, Yamaguchi A, Iimura T.

Original paper Hox genes control vertebrate body elongation by collinear Wnt repression.

eLife.， 2015； 26-Feb：4

DOI:10.7554/eLife.04379

Denans N. Iimura T. Pourquie O.

Original paper Rosmarinic acid exerts an anti-osteoporotic effect in the RANKL-induced mouse model of bone loss by promotion of osteoblastic differentiation and inhibition of osteoclastic differentiation.

Mol. Nutr. Food Res..， 2015； 59：386–400

DOI:10.1002/mnfr

Lee JW, Asai M, Jeon SK, Iimura T, Yonezawa T, Cha BY, Woo JT, Yamaguchi A.

Original paper Members of the Plant CRK-superfamily are Capable of trans-/auto-Phosphorylation of Tyrosine Residues.

J Biol Chem.， 2015； 290：16665-16677

DOI:10.1074/jbc.M114.617274

Nemoto K, Takemori N, Seki M, Shinozaki K, Sawasaki T

Original paper An essential role of the arginine vasotocin system in mate-guarding behaviors in triadic relationships of medaka fish (Oryzias latipes).

PLoS Genet.， 2015； 11(2)：e1005009

DOI:10.1371/journal.pgen.1005009

Yokoi S, Okuyama T, Kamei Y, Naruse K, Taniguchi Y, Ansai S, Kinoshita M, Young LJ, Takemori N, Kubo T, and Takeuchi H

Original paper Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.

J Exp Med..， 2014； 211：1857-74

DOI:10.1084/jem.20130791

Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H.

Original paper The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.

Nat Commun..， 2014； 2：2.677083333

DOI:10.1038/ncomms4555

Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T, Yamashita M.

Original paper A novel function of interferon regulatory factor-1: inhibition of Th2 cells by down-regulating the Il4 gene during Listeria infection.

Int Immunol..， 2015； 27：143-52

DOI:10.1093/intimm/dxu092

Maruyama S, Kanoh M, Matsumoto A, Kuwahara M, Yamashita M, Asano Y.

Original paper Hydroxylation of Methylated DNA by TET1 in Chondrocyte Differentiation of C3H10T1/2 Cells.

Biochem Biophys Rep.， 2016； 5：134-140

DOI:10.1016/j.bbrep.2015.11.009

Ito R, Shimada H, Yazawa K, Sato I, Imai Y, Sugawara A, Yokoyama A.

Original paper A novel mitosomal β-barrel outer membrane protein in Entamoeba.

Sci. Rep..， 2015； 5：8545

DOI:10.1038/srep08545

Herbert Santos, Kenichiro Imai, Takashi Makiuchi, Kentaro Tomii, Paul Horton, Akira Nozawa, Mohamed Ibrahim, Yuzuru Tozawa, and Tomoyoshi Nozaki

Original paper The rodent malaria lactate dehydrogenase assay provides a high throughput solution for in vivo vaccine studies

Parasitol Int.， 2015； 64：60-63

DOI:10.1016/j.parint.2015.02.001

Otsuki H, Yokouchi Y, Iyoku N, Tachibana M, Tsuboi T, Torii M

Original paper Plasmodium vivax gametocyte proteins, Pvs48/45 and Pvs47, induce transmission-reducing antibodies by DNA immunization

Vaccine.， 2015； 33：1901-1908

DOI:10.1016/j.vaccine.2015.03.008

Tachibana M, Suwanabun N, Kaneko O, Iriko H, Otsuki H, Sattabongkot J, Kaneko A, Herrera S, Torii M, Tsuboi T

Original paper Imaging of the subsurface structures of “unroofed” Plasmodium falciparum-infected erythrocytes

Exp Parasitol.， 2015； 153：174-179

DOI:10.1016/j.exppara.2015.03.021

Hayakawa EH, Tokumasu F, Usukura J, Matsuoka H, Tsuboi T, Wellems TE

Original paper Naturally-acquired cellular immune response against Plasmodium vivax merozoite surface protein-1 paralog antigen

Malar J.， 2015； 14：159

DOI:10.1186/s12936-015-0681-8

Changrob S, Leepiyasakulchai C, Tsuboi T, Cheng Y, Lim CS, Chootong P, Han ET

Original paper Antigenicity and immunogenicity of PvRALP1, a novel Plasmodium vivax rhoptry neck protein

Malar J.， 2015； 14：186

DOI:10.1186/s12936-015-0698-z

Cheng Y, Li J, Ito D, Kong DH, Ha KS, Lu F, Wang B, Sattabongkot J, Lim CS, Tsuboi T, Han ET

Original paper Immunoprofiling of the tryptophan-rich antigen family in Plasmodium vivax

Infect Immun.， 2015； 83(8)：3083-95

DOI:10.1128/IAI.03067-14

Wang B, Lu F, Cheng Y, Chen JH, Jeon HY, Ha KS, Cao J, Nyunt MH, Han JH, Lee SK, Kyaw MP, Sattabongkot J, Takashima E, Tsuboi T, Han ET

Original paper Characterization of Plasmodium vivax Early Transcribed Membrane Protein 11.2 and Exported Protein 1

PLoS One.， 2015； 10：e0127500

DOI:10.1371/journal.pone.0127500

Cheng Y, Lu F, Lee SK, Kong DH, Ha KS, Wang B, Sattabongkot J, Tsuboi T, Han ET

Original paper Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

PLoS One.， 2015； 10：e0136109

DOI:10.1371/journal.pone.0136109

Aguiar JC, Bolton J, Wanga J, Sacci JB, Iriko H, Mazeika JK, Han ET, Limbach K, Patterson NB, Sedegah M, Cruz AM, Tsuboi T, Hoffman SL, Carucci D, Hollingdale MR, Villasante ED, Richie TL

Original paper Angiographic and optical coherence tomography insights into bioresorbable scaffold thrombosis: single-center experience.

Circ Cardiovasc Interv..， 2015； 8：pii: e002369

DOI:10.1161/CIRCINTERVENTIONS.114.002369

Karanasos A, Van Mieghem N, van Ditzhuijzen N, Felix C, Daemen J, Autar A, Onuma Y, Kurata M, Diletti R, Valgimigli M, Kauer F, van Beusekom H, de Jaegere P, Zijlstra F, van Geuns RJ, Regar E.

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