Achievements

Original paper Antibody responses to Plasmodium falciparum and Plasmodium vivax blood-stage and sporozoite antigens in the postpartum period.

Sci Rep..， 2016； 6：32159

DOI:10.1038/srep32159

McLean AR, Boel ME, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJ

Original paper Identification of a reticulocyte-specific binding domain of Plasmodium vivax reticulocyte-binding protein 1 that is homologous to the PfRh4 erythrocyte-binding domain.

Sci Rep..， 2016； 6：26993

DOI:10.1038/srep26993

Han JH, Lee SK, Wang B, Muh F, Nyunt MH, Na S, Ha KS, Hong SH, Park WS, Sattabongkot J, Tsuboi T, Han ET

Original paper Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria.

Malar J..， 2016； 15：258

DOI:10.1186/s12936-016-1296-4

Duffy MF, Noviyanti R, Tsuboi T, Feng ZP, Trianty L, Sebayang BF, Takashima E, Sumardy F, Lampah DA, Turner L, Lavstsen T, Fowkes FJ, Siba P, Rogerson SJ, Theander TG, Marfurt J, Price RN, Anstey NM, Brown GV, Papenfuss AT

Original paper Identification of three ookinete-specific genes and evaluation of their transmission-blocking potentials in Plasmodium berghei.

Vaccine.， 2016； 34：244927

DOI:10.1016/j.vaccine.2016.04.011

Zheng W, Kou X, Du Y, Liu F, Yu C, Tsuboi T, Fan Q, Luo E, Cao Y, Cui L

Original paper Naturally-Acquired Immune Response against Plasmodium vivax Rhoptry-Associated Membrane Antigen.

PLoS One.， 2016； 11：e0153110

DOI:10.1371/journal.pone.0153110

Changrob S, Wang B, Han JH, Lee SK, Nyunt MH, Lim CS, Tsuboi T, Chootong P, Han ET

Original paper Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting.

Sci Rep..， 2016； 6：20859

DOI:10.1038/srep20859

Charnaud SC, McGready R, Herten-Crabb A, Powell R, Guy A, Langer C, Richards JS, Gilson PR, Chotivanich K, Tsuboi T, Narum DL, Pimanpanarak M, Simpson JA, Beeson JG, Nosten F, Fowkes FJ

Original paper Multiple Plasmodium falciparum Merozoite Surface Protein 1 Complexes Mediate Merozoite Binding to Human Erythrocytes.

J Biol Chem.， 2016； 291：7703-15

DOI:10.1074/jbc.M115.698282

Lin CS, Uboldi AD, Epp C, Bujard H, Tsuboi T, Czabotar PE, Cowman AF

Original paper The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells.

PLoS One..， 2016； 10；11：e0157395

DOI:10.1371/journal.pone.0157395

Yasuoka T, Kuwahara M, Yamada T, Maruyama S, Suzuki J, Taniguchi M, Yasukawa M, Yamashita M.

Original paper Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis.

ScientificWorldJournal..， 2016； 2016：2597376

DOI:10.1155/2016/2597376

Iwasaki T, Kaneko N, Ito Y, Takeda H, Sawasaki T, Heike T, Migita K, Agematsu K, Kawakami A, Morikawa S, Mokuda S, Kurata M, Masumoto J.

Original paper Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Nat Commun..， 2016； 7：12547

DOI:10.1038/ncomms12547

Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F.

Original paper AGIA Tag System Based on a High Affinity Rabbit Monoclonal Antibody against Human Dopamine Receptor D1 for Protein Analysis.

PLoS One..， 2016； 11：e0156716

DOI:10.1371/journal.pone.0156716

Yano T, Takeda H, Uematsu A, Yamanaka S, Nomura S, Nemoto K, Iwasaki T, Takahashi H, Sawasaki T.

Original paper Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins.

PLoS One..， 2016； 11：e0156718

DOI:10.1371/journal.pone.0156718

Takahashi H, Uematsu A, Yamanaka S, Imamura M, Nakajima T, Doi K, Yasuoka S, Takahashi C, Takeda H, Sawasaki T.

Original paper Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication.

PLoS Pathog..， 2016； 12：e1005357

DOI:10.1371/journal.ppat.1005357

Suzuki Y, Chin WX, Han Q, Ichiyama K, Lee CH, Eyo ZW, Ebina H, Takahashi H, Takahashi C, Tan BH, Hishiki T, Ohba K, Matsuyama T, Koyanagi Y, Tan YJ, Sawasaki T, Chu JJ, Vasudevan SG, Sano K, Yamamoto N.

Original paper Involvement of the 3’ Untranslated Region in Encapsidation of the Hepatitis C Virus.

PLoS Pathog..， 2016； 12：e1005441

DOI:10.1371/journal.ppat.1005441

Shi G, Ando T, Suzuki R, Matsuda M, Nakashima K, Ito M, Omatsu T, Oba M, Ochiai H, Kato T, Mizutani T, Sawasaki T, Wakita T, Suzuki T.

Original paper H11/HSPB8 Restricts HIV-2 Vpx to Restore the Anti-Viral Activity of SAMHD1.

Front Microbiol..， 2016； 7：883

DOI:10.3389/fmicb.2016.00883

Kudoh A, Miyakawa K, Matsunaga S, Matsushima Y, Kosugi I, Kimura H, Hayakawa S, Sawasaki T, Ryo A.

Original paper Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage.

Biochim Biophys Acta..， 2016； S0167-4889：30215-4

DOI:10.1016/j.bbamcr.2016.08.010

Sakamaki K, Ishii TM, Sakata T, Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Jung SK, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N.

Original paper Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.

Immunology.， 2016； 147：476-87

DOI:10.1111/imm.12580

Suzuki J, Maruyama S, Tamauchi H, Kuwahara M, Horiuchi M, Mizuki M, Ochi M, Sawasaki T, Zhu J, Yasukawa M, Yamashita M.

Original paper Identification of Nedd9 as a TGF-β-Smad2/3 Taget Gene Involved in RANKL-Induced Osteoclastgenesis by Comprehensive Analysis

PLoS One..， 2016； 11(6)：e0157992

DOI:10.1371/journal.pone.0157992

Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, Matsumoto T, Imai Y, Seo S, Kurokawa M, Tsutsumi S, Kadono Y, Morimoto C, Aburatani H, Miyamoto T, Tanaka S.

Original paper MyoD reprogramming requires Six1 and Six4 homeoproteins: genome-wide cis-regulatory module analysis.

Nucleic Acids Res..， 2016；：

DOI:10.1093/nar/gkw512

Santolini M, Sakakibara I, Gauthier M, Ribas-Aulinas F, Takahashi H, Sawasaki T, Mouly V, Concordet JP, Defossez PA, Hakim V, Maire P.

Original paper High-throughput production of a stable isotope-labeled peptide library for targeted proteomics using a wheat germ cell-free synthesis system

Mol. BioSyst..， 2016； 12(8)：2389-2393

DOI:10.1039/c6mb00209a

Takemori N, Takemori A, Tanaka Y, Ishizaki J, Hasegawa H, Shiraishi A, Ohashi Y.

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