Achievements

Original paper Netrin-1 Augments Chemokinesis in CD4+ T Cells In Vitro and Elicits a Proinflammatory Response In Vivo.

J Immunol..， 2016； 197(4)：1389-98

DOI:10.4049/jimmunol.1502432

Boneschansker L, Nakayama H, Eisenga M, Wedel J, Klagsbrun M, Irimia D, Briscoe DM.

Original paper Neuropilin 1 Receptor Is Up-Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma.

Am J Pathol..， 2016； 186(4)：1055-64

DOI:10.1016/j.ajpath.2015.11.021

Shahrabi-Farahani S, Gallottini M, Martins F, Li E, Mudge DR, Nakayama H, Hida K, Panigrahy D, D'Amore PA, Bielenberg DR.

Original paper Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A).

J Biol Chem..， 2016； 291(20)：10490-500

DOI:10.1074/jbc.M115.683201

Nishida-Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, Fukuda S, Sakaue T, Shirakata Y, Sayama K, Hashimoto K, Detmar M, Higashiyama S, Hirakawa S.

Original paper Quantitative imaging of fibrotic and morphological changes in liver of non-alcoholic steatohepatitis (NASH) model mice by second harmonic generation (SHG) and auto-fluorescence (AF) imaging using two-photon excitation microscopy (TPEM).

Biochemistry and Biophysics Reports.， 2016； 8：277-283

DOI:10.1016/j.bbrep.2016.09.010

Yamamoto S, Oshima Y, Saitou T, Watanabe T, Miyake T, Yoshida O, Tokumoto Y, Abe M, Matsuura B, Hiasa Y, Imamura T.

Original paper Structural analysis and homology modeling of members of smt-like operon from thermophilic cyanobacterium Thermosynechococcus elongatus BP-1

J.Proteins .Proteomics.， 2016； 7：221-230

DOI:------

Shelake RM, Morita EH, Hayashi H

Original paper Heterologous expression of thermolabile proteins enhances thermotolerance in Escherichia coli

Adv. Microbiol..， 2016； 6：602-612

DOI:10.4236/aim.2016.69060

Ueda Y, Yamauchi S, Fukata S, Okuyama H, Morita EH, Shelake RM, Hayashi H

Original paper Administration frequency as well as dosage of PTH are associated with development of cortical porosity in ovariectomized rats

Bone Research.， 2017； 5：17002

DOI:10.1038/boneres.2017.2

Takakura A, Lee JW, Hirano K, Isogai Y, Ishizuya T, and Takao-Kawabata R, Iimura T

Original paper An ATP generation system for in vitro motility assay

Chem. Lett..， 2017； 46：178-180

DOI:10.1246/cl.160903

Kabir, A. M. R., Ito, M., Uenishi. K., Anan, S., Konagaya, A., Sada. K., Sugiura, M., and Kakugo, A.

Original paper Local co-application of zoledronate Promotes long-term maintenance of newly formed bone induced by recombinant human bone morphogenetic protein 2.

Biochem Biophys Res Commun..， 2016； 480(3)：314-320

DOI:10.1016/j.bbrc.2016.10.034

Ichikawa K, Ohta Y, Mamoto K, Mizokawa S, Minoda Y, Imai Y, Takaoka K, Nakamura H.

Original paper Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine

Sci. Rep..， 2016； 6：35762

DOI:10.1038/srep35762

Maekawa M, Lee M, Wei K, Ridgway ND, Fairn GD.

Original paper Corrigendum to “Influence of Histidine-198 of the D1 subunit on the properties of the primary electron donor, P680, of Photosystem II in Thermosynechococcus elongatus”

Biochim. Biophys. Acta (Bioenergetics).， 2016； 1853：1943-1948

DOI:10.1016/j.bbabio.2016.09.012

Sugiura, M., Ozaki, Y., Rappaport F., and Boussac A.

Original paper CRACM3 regulates the stability of non-excitable exocytotic vesicle fusion pores in a Ca2+-independent manner via molecular interaction with syntaxin4,

Scientific Reports.， 2016； 6：28133

DOI:10.1038/srep28133

Shuang Liu, Muhammad Novrizal Abdi Sahid, Erika Takemasa, Takeshi Kiyoi, Miyuki Kuno, Yusuke Oshima, Kazutaka Maeyama

Original paper Short-term intermittent administration of parathyroid hormone facilitates osteogenesis by different mechanisms in cancellous and cortical bone

Bone Reports.， 2016； 5：44756

DOI:10.1016/j.bonr.2016.01.002

Ogura K, Iimura T, Makino Y, Sugie-Oya A, Takakura A, Takao-Kawabata R, Ishizuya T, Moriyama K, Akira Yamaguchi Y.

Original paper Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice.

Sci Rep..， 2016； 6：28882

DOI:10.1038/srep28882

Pei Z, Okura T, Nagao T, Enomoto D, Kukida M, Tanino A, Miyoshi K, Kurata M, Higaki J.

Original paper Plasma thrombin-cleaved osteopontin as a potential biomarker of acute atherothrombotic ischemic stroke.

Hypertens Res..， 2016； 40：61–66

DOI:10.1038/hr.2016.110

Ozaki S, Kurata M, Kumon Y, Matsumoto S, Tagawa M, Watanabe H, Ohue S, Higaki J, Ohnishi T.

Original paper Familial Mediterranean fever is no longer a rare disease in Japan.

Arthritis Res Ther..， 2016； 18：175

DOI:10.1186/s13075-016-1071-5

Migita K, Izumi Y, Jiuchi Y, Iwanaga N, Kawahara C, Agematsu K, Yachie A, Masumoto J, Fujikawa K, Yamasaki S, Nakamura T, Ubara Y, Koga T, Nakashima Y, Shimizu T, Umeda M, Nonaka F, Yasunami M, Eguchi K, Yoshiura K, Kawakami A.

Original paper Multiple Serum Cytokine Profiling to Identify Combinational Diagnostic Biomarkers in Attacks of Familial Mediterranean Fever.

Medicine (Baltimore)..， 2016； 95：e3449

DOI:10.1097/MD.0000000000003449

Koga T, Migita K, Sato S, Umeda M, Nonaka F, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Masumoto J, Agematsu K, Yachie A, Yoshiura K, Eguchi K, Kawakami A.

Original paper IL-18 serum concentration is markedly elevated in typical familial Mediterranean fever with M694I mutation and can distinguish it from atypical type.

Mod Rheumatol..， 2016； 26：315-317

DOI:10.3109/14397595.2014.988861

Yamazaki T, Shigemura T, Kobayashi N, Honda K, Yazaki M, Masumoto J, Migita K, Agematsu K

Original paper Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant Behçets disease.

RMD Open.， 2016； 2：e000223

DOI:10.1136/rmdopen-2015-000223

Shigemura T, Kaneko N, Kobayashi N, Kobayashi K, Takeuchi Y, Nakano N, Masumoto J, Agematsu K.

Original paper Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

Skelet Muscle..， 2016； 6(1)：30

DOI:10.1186/s13395-016-0102-x

Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, Guernec A, Sakamoto K, Maire P.

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