Achievements

Original paper Artificial OFF-Riboswitches That Downregulate Internal Ribosome Entry without Hybridization Switches in a Eukaryotic Cell-Free Translation System

ACS Synth. Biol..， 2017； 6：1656-1662

DOI:10.1021/acssynbio.7b00124

Ogawa A, Masuoka H, Ota T

Original paper Perivascular Adipose Tissue Angiotensin II Type 1 Receptor Promotes Vascular Inflammation and Aneurysm Formation.

Hypertension..， 2017； 117：9512

DOI:10.1161/HYPERTENSIONAHA.117.09512

Sakaue T, Suzuki J, Hamaguchi M, Suehiro C, Tanino A, Nagao T, Uetani T, Aono J, Nakaoka H, Kurata M, Sakaue T, Okura T, Yasugi T, Izutani H, Higaki J, Ikeda S.

Original paper The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells.

Si. Rep..， 2017； 7：42845

DOI:10.1016/j.surg.2016.12.017

Sakaue T, Sakakibara I, Uesugi T, Fujisaki A, Nakashiro KI, Hamakawa H, Kubota E, Joh T, Imai YK, Izutani H, Higashiyama S.

Original paper Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.

PLoS One..， 2017； 12：e0177343

DOI:10.1371/journal.pone.0177343

Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.

Original paper Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons.

PLoS One..， 2017； 12：e0174780

DOI:10.1371/journal.pone.0174780

Iwakura Y, Wang R, Inamura N, Araki K, Higashiyama S, Takei N, Nawa H.

Original paper Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts

J Bone Miner Res.， 2017； 32：2074–2086

DOI:10.1002/jbmr.3175

Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N, Udagawa N

Original paper Acute development of cortical porosity and endosteal naïve bone formation from the daily but not weekly short-term administration of PTH in rabbit

PLoS One.， 2017； 12(4)：e0175329

DOI:10.1371/journal.pone.0175329

Yamane H, Takakura A, Shimadzu Y, Kodama T, Lee JW, Isogai Y, Ishizuya T, Takao-Kawabata R, Iimura T

Original paper Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction

Journal of Controlled Release.， 2017； 260：44572

DOI:10.1016/j.jconrel.2017.05.024

Susanne M. Krug, Tomohiro Hayaishi, Daisuke Iguchi, Akihiro Watari, Azusa Takahashi, Michael Fromm, Masahiro Nagahama, Hiroyuki Takeda, Yoshiaki Okada, Tatsuya Sawasaki, Takefumi Doi, Kiyohito Yagi, Masuo Kondoh

Original paper CP5 system, for simple and highly efficient protein purification with a C-terminal designed mini tag

PLOS ONE.， 2017；：

DOI:10.1371/journal.pone.0178246

Hiroyuki Takeda, Wei Zhou, Kohki Kido, Ryoji Suno, Takahiro Iwasaki, Takuya Kobayashi, Tatsuya Sawasaki

Original paper Crystal structure and redox properties of a novel cyanobacterial heme-protein with a His/Cys heme axial ligation and a per-arnt-sim (PAS)-like domain

Ｊ. Biol. Chem..， 2017； 292：9599-9612

DOI:10.1074/jbc.M116.746263

Motomura, T., Suga, M., Hienerwadel, R., Nakagawa, A., Lai, T.-L., Nitschke, W., Sugiura, M, Boussac, A. and Shen, J.-R.

Original paper Early diagnosis of early-onset sarcoidosis: a case report with functional analysis and review of the literature

Clin Rheumatol.， 2017； in press：in press

DOI:10.1007/s10067-017-3544-6

Takeuchi Y, Shigemura T, Kobayashi N, Kaneko N, Iwasaki T, Minami K, Kobayashi K, Masumoto J, Agematsu K

Original paper Interaction between RNF8 and DYRK2 is required for the recruitment of DNA repair molecules to DNA double-strand breaks.

FEBS Lett..， 2017；：

DOI:10.1002/1873-3468.12596

Yamamoto T, Taira Nihira N, Yogosawa S, Aoki K, Takeda H, Sawasaki T, Yoshida K.

Original paper Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop.

Nat Commun..， 2016； 7：12596

DOI:10.1038/ncomms12596

Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M.

Original paper HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.

PLoS Pathog..， 2017； 13：e1006162

DOI:10.1371/journal.ppat.1006162

Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, Inoue JI.

Original paper OsMYC2, an essential factor for JA-inductive sakuranetin production in rice, interacts with MYC2-like proteins that enhance its transactivation ability.

Sci Rep..， 2017； 7：40175

DOI:10.1038/srep40175

Ogawa S, Miyamoto K, Nemoto K, Sawasaki T, Yamane H, Nojiri H, Okada K.

Original paper Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

Proc Natl Acad Sci USA.， 2017； 114：3515-3520

DOI:10.1073/pnas.1615875114

Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O'Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ

Original paper Antibody responses to Plasmodium falciparum and Plasmodium vivax and prospective risk of Plasmodium spp. infection postpartum

Am J Trop Med Hyg.， 2017； 96：1197-1204

DOI:10.4269/ajtmh.16-0690

McLean ARD, Boel ME, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJI

Original paper Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

Sci Rep..， 2017； 7：46086

DOI:10.1038/srep46086

Morita M, Takashima E*, Ito D, Miura K, Thongkukiatkul A, Diouf A, Fairhurst RM, Diakite M, Long CA, Torii M, Tsuboi T

Original paper Plant Aurora kinases interact with and phosphorylate transcription factors.

J Plant Res..， 2016； 129：1165-1178

DOI:10.1007/s10265-016-0860-x

Takagi M, Sakamoto T, Suzuki R, Nemoto K, Obayashi T, Hirakawa T, Matsunaga TM, Kurihara D, Nariai Y, Urano T, Sawasaki T, Matsunaga S.

Original paper Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda

Vaccine.， 2017； 35：873-881

DOI:10.1016/j.vaccine.2017.01.001

Kanoi BN, Takashima E, Morita M, White MT, Palacpac NM, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T

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