ACHIEVEMENTS

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英文原著 Artificial OFF-Riboswitches That Downregulate Internal Ribosome Entry without Hybridization Switches in a Eukaryotic Cell-Free Translation System

ACS Synth. Biol.., 2017; 6:1656-1662
DOI:10.1021/acssynbio.7b00124
Ogawa A, Masuoka H, Ota T

英文原著 Perivascular Adipose Tissue Angiotensin II Type 1 Receptor Promotes Vascular Inflammation and Aneurysm Formation.

Hypertension.., 2017; 117:9512
DOI:10.1161/HYPERTENSIONAHA.117.09512
Sakaue T, Suzuki J, Hamaguchi M, Suehiro C, Tanino A, Nagao T, Uetani T, Aono J, Nakaoka H, Kurata M, Sakaue T, Okura T, Yasugi T, Izutani H, Higaki J, Ikeda S.

英文原著 The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells.

Si. Rep.., 2017; 7:42845
DOI:10.1016/j.surg.2016.12.017
Sakaue T, Sakakibara I, Uesugi T, Fujisaki A, Nakashiro KI, Hamakawa H, Kubota E, Joh T, Imai YK, Izutani H, Higashiyama S.

英文原著 Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.

PLoS One.., 2017; 12:e0177343
DOI:10.1371/journal.pone.0177343
Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.

英文原著 Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons.

PLoS One.., 2017; 12:e0174780
DOI:10.1371/journal.pone.0174780
Iwakura Y, Wang R, Inamura N, Araki K, Higashiyama S, Takei N, Nawa H.

英文原著 Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts

J Bone Miner Res., 2017; 32:2074–2086
DOI:10.1002/jbmr.3175
Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N, Udagawa N

英文原著 Acute development of cortical porosity and endosteal naïve bone formation from the daily but not weekly short-term administration of PTH in rabbit

PLoS One., 2017; 12(4):e0175329
DOI:10.1371/journal.pone.0175329
Yamane H, Takakura A, Shimadzu Y, Kodama T, Lee JW, Isogai Y, Ishizuya T, Takao-Kawabata R, Iimura T

英文原著 Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction

Journal of Controlled Release., 2017; 260:44572
DOI:10.1016/j.jconrel.2017.05.024
Susanne M. Krug, Tomohiro Hayaishi, Daisuke Iguchi, Akihiro Watari, Azusa Takahashi, Michael Fromm, Masahiro Nagahama, Hiroyuki Takeda, Yoshiaki Okada, Tatsuya Sawasaki, Takefumi Doi, Kiyohito Yagi, Masuo Kondoh

英文原著 CP5 system, for simple and highly efficient protein purification with a C-terminal designed mini tag

PLOS ONE., 2017; :
DOI:10.1371/journal.pone.0178246
Hiroyuki Takeda, Wei Zhou, Kohki Kido, Ryoji Suno, Takahiro Iwasaki, Takuya Kobayashi, Tatsuya Sawasaki

英文原著 Crystal structure and redox properties of a novel cyanobacterial heme-protein with a His/Cys heme axial ligation and a per-arnt-sim (PAS)-like domain

J. Biol. Chem.., 2017; 292:9599-9612
DOI:10.1074/jbc.M116.746263
Motomura, T., Suga, M., Hienerwadel, R., Nakagawa, A., Lai, T.-L., Nitschke, W., Sugiura, M, Boussac, A. and Shen, J.-R.

英文原著 Early diagnosis of early-onset sarcoidosis: a case report with functional analysis and review of the literature

Clin Rheumatol., 2017; in press:in press
DOI:10.1007/s10067-017-3544-6
Takeuchi Y, Shigemura T, Kobayashi N, Kaneko N, Iwasaki T, Minami K, Kobayashi K, Masumoto J, Agematsu K

英文原著 Interaction between RNF8 and DYRK2 is required for the recruitment of DNA repair molecules to DNA double-strand breaks.

FEBS Lett.., 2017; :
DOI:10.1002/1873-3468.12596
Yamamoto T, Taira Nihira N, Yogosawa S, Aoki K, Takeda H, Sawasaki T, Yoshida K.

英文原著 Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop.

Nat Commun.., 2016; 7:12596
DOI:10.1038/ncomms12596
Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M.

英文原著 HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.

PLoS Pathog.., 2017; 13:e1006162
DOI:10.1371/journal.ppat.1006162
Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, Inoue JI.

英文原著 OsMYC2, an essential factor for JA-inductive sakuranetin production in rice, interacts with MYC2-like proteins that enhance its transactivation ability.

Sci Rep.., 2017; 7:40175
DOI:10.1038/srep40175
Ogawa S, Miyamoto K, Nemoto K, Sawasaki T, Yamane H, Nojiri H, Okada K.

英文原著 Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

Proc Natl Acad Sci USA., 2017; 114:3515-3520
DOI:10.1073/pnas.1615875114
Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O'Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ

英文原著 Antibody responses to Plasmodium falciparum and Plasmodium vivax and prospective risk of Plasmodium spp. infection postpartum

Am J Trop Med Hyg., 2017; 96:1197-1204
DOI:10.4269/ajtmh.16-0690
McLean ARD, Boel ME, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJI

英文原著 Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

Sci Rep.., 2017; 7:46086
DOI:10.1038/srep46086
Morita M, Takashima E*, Ito D, Miura K, Thongkukiatkul A, Diouf A, Fairhurst RM, Diakite M, Long CA, Torii M, Tsuboi T

英文原著 Plant Aurora kinases interact with and phosphorylate transcription factors.

J Plant Res.., 2016; 129:1165-1178
DOI:10.1007/s10265-016-0860-x
Takagi M, Sakamoto T, Suzuki R, Nemoto K, Obayashi T, Hirakawa T, Matsunaga TM, Kurihara D, Nariai Y, Urano T, Sawasaki T, Matsunaga S.

英文原著 Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda

Vaccine., 2017; 35:873-881
DOI:10.1016/j.vaccine.2017.01.001
Kanoi BN, Takashima E, Morita M, White MT, Palacpac NM, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T