研究業績｜愛媛大学プロテオサイエンスセンター

英文原著 Arkadia enhances BMP signaling through ubiquitylation and degradation of Smad6

The Journal of Biochemistry.， 2015； 158：61-71

DOI:10.1093/jb/mvv024

Yutaro Tsubakihara, Atsuhiko Hikita, Shin Yamamoto, Sachi Matsushita, Natsuki Matsushita, Yusuke Oshima, Keiji Miyazawa and Takeshi Imamura

英文原著 Evaluation of Injured Axons Using Two-Photon Excited Fluorescence Microscopy after Spinal Cord Contusion Injury in YFP-H Line Mice

International Journal of Molecular Sciences.， 2015； 16：15785-99

DOI:10.3390/ijms160715785

Hideki Horiuchi, Yusuke Oshima, Tadanori Ogata, Tadao Morino, Seiji Matsuda, Hiromasa Miura and Takeshi Imamura

英文原著 Analyses of bone modeling and remodeling using in vitro reconstitution system with two-photon microscopy

Bone.， 2015； 76：44698

DOI:10.1016/j.bone.2015.02.030

Atsuhiko Hikita, Tadahiro Iimura, Yusuke Oshima, Takashi Saitou, Shin Yamamoto and Takeshi Imamura

英文原著 Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system

Scientific Reports.， 2016； 6：20209

DOI:10.1038/srep20209

Shinji Fukuda, Hisayo Nishida-Fukuda, Daisuke Nanba, Koh-ichi Nakashiro, Hironao Nakayama, Hiroyuki Kubota, Shigeki Higashiyama

英文原著 Rotation is the primary motion of paired human epidermal keratinocytes.

J Dermatol Sci..， 2015； 79：194-202

DOI:10.1016/j.jdermsci.2015.05.008

Tate S, Imai M, Matsushita N, Nishimura EK, Higashiyama S, Nanba D.

英文原著 Cell motion predicts human epidermal stemness.

J Cell Biol..， 2015； 209：305-15

DOI:10.1083/jcb.201409024

Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y.

英文原著 Long‑term exposure to leptin enhances the growth of prostate cancer cells.

Int J Oncol..， 2015； 46：1535-42

DOI:10.3892/ijo.2015.2845

Noda T, Kikugawa T, Tanji N, Miura N, Asai S, Higashiyama S, Yokoyama M.

英文原著 Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo.

Sci Rep..， 2015； 5：11789

DOI:10.1038/srep11789

Nakayama H, Bruneau S, Kochupurakkal N, Coma S, Briscoe DM, Klagsbrun M.

英文原著 Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins.

Biochem Biophys Res Commun..， 2015； 464：126-32

DOI:10.1016/j.bbrc.2015.06.087

Nakayama H, Huang L, Kelly RP, Oudenaarden CR, Dagher A, Hofmann NA, Moses MA, Bischoff J, Klagsbrun M.

英文原著 Occurrence of trans monounsaturated and polyunsaturated fatty acids in Colwellia psychrerythraea strain 34H

J. Basic Microbiol..， 2015； 55：838-845

DOI:10.1002/jobm.201400815

Hashimoto M, Orikasa Y, Hayashi H, atanabe K, Yoshida K, and Okuyama H

英文原著 High-throughput synthesis of stable isotope-labeled transmembrane proteins for targeted transmembrane proteomics using a wheat germ cell-free protein synthesis system

Mol Biosyst..， 2015； 11：361-365

DOI:10.1039/c4mb00556b

Takemori N, Takemori A, Matsuoka K, Morishita R, Matsushita N, Aoshima M, Takeda H, Sawasaki T, Endo Y, Higashiyama S

英文原著 Oral mucosal fibroblasts overexpressing BMP-2 differentiate into osteoblasts and participate in new bone formation during bone regeneration.

Journal of Oral Biosciences.， 2015； 57：118–123

DOI:10.1016/j.job.2015.01.001

Lin Z, Iimura T, Kasugai S, Yamaguchi A.

英文原著 Changes in the spatial distribution of sclerostin in the osteocytic lacuno-canalicular system in alveolar bone due to orthodontic forces, as detected on multimodal confocal fluorescence imaging analyses.

Arch Oral Biol..， 2015； 60：45-54

DOI:10.1016/j.archoralbio

Nishiyama Y, Matsumoto T, Lee JW, Saitou T, Imamura T, Moriyama K, Yamaguchi A, Iimura T.

英文原著 Hox genes control vertebrate body elongation by collinear Wnt repression.

eLife.， 2015； 26-Feb：4

DOI:10.7554/eLife.04379

Denans N. Iimura T. Pourquie O.

英文原著 Rosmarinic acid exerts an anti-osteoporotic effect in the RANKL-induced mouse model of bone loss by promotion of osteoblastic differentiation and inhibition of osteoclastic differentiation.

Mol. Nutr. Food Res..， 2015； 59：386–400

DOI:10.1002/mnfr

Lee JW, Asai M, Jeon SK, Iimura T, Yonezawa T, Cha BY, Woo JT, Yamaguchi A.

英文原著 Members of the Plant CRK-superfamily are Capable of trans-/auto-Phosphorylation of Tyrosine Residues.

J Biol Chem.， 2015； 290：16665-16677

DOI:10.1074/jbc.M114.617274

Nemoto K, Takemori N, Seki M, Shinozaki K, Sawasaki T

英文原著 An essential role of the arginine vasotocin system in mate-guarding behaviors in triadic relationships of medaka fish (Oryzias latipes).

PLoS Genet.， 2015； 11(2)：e1005009

DOI:10.1371/journal.pgen.1005009

Yokoi S, Okuyama T, Kamei Y, Naruse K, Taniguchi Y, Ansai S, Kinoshita M, Young LJ, Takemori N, Kubo T, and Takeuchi H

英文原著 Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.

J Exp Med..， 2014； 211：1857-74

DOI:10.1084/jem.20130791

Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H.

英文原著 The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.

Nat Commun..， 2014； 2：2.677083333

DOI:10.1038/ncomms4555

Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T, Yamashita M.

英文原著 A novel function of interferon regulatory factor-1: inhibition of Th2 cells by down-regulating the Il4 gene during Listeria infection.

Int Immunol..， 2015； 27：143-52

DOI:10.1093/intimm/dxu092

Maruyama S, Kanoh M, Matsumoto A, Kuwahara M, Yamashita M, Asano Y.

ACHIEVEMENTS 研究業績

SEARCH ACHIEVEMENTS