研究業績｜愛媛大学プロテオサイエンスセンター

英文原著 Trehalose prevents IL-4/IL-13-induced skin barrier impairment by suppressing IL-33 expression and increasing Nrf2 activation in human keratinocytes in vitro

J Invest Dermatol.， 2024； S0022-202X(24)：02175-4

DOI:10.1016/j.jid.2024.08.038

Xiuju Dai, Yoichi Mizukami, Kenji Watanabe, Teruko Tsuda, Mutsumi Shidahara, Satoshi Yoshida, Kazuki Yatsuzuka, Ken Shiraishi, Hideki Mori, Masamoto Murakami, Ryosuke Kawakami, Takeshi Imamura, Yasuhiro Fujisawa, Jun Muto

英文原著 Enhanced light-sheet illumination by a multi-layered stair-step phase mask

Jpn. J. Appl. Phys.， 2024； 63：108002

DOI:10.35848/1347-4065/ad83db

Takashi Saitou, Takeshi Imamura

英文原著 Multiplexed spatial imaging at the single-cell level reveals mutually exclusive expression of B7 family proteins

Lab Invest.， 2024； 104(10)：102131

DOI:10.1016/j.labinv.2024.102131

Kazunori Shojo, Nobuyuki Tanaka, Tetsushi Murakami, Tadatsugu Anno, Yu Teranishi, Kimiharu Takamatsu, Shuji Mikami, Takeshi Imamura, Kazuhiro Matsumoto, Mototsugu Oya

英文原著 Heterozygous mutations in the straitjacket region of the latency-associated peptide domain of TGFB2 cause Camurati-Engelmann disease type II

J Hum Genet.， 2024； 69(11)：599-605

DOI:10.1038/s10038-024-01274-1

Zheng Wang, Mitsuhiro Kometani, Leonid Zeitlin, Yael Wilnai, Akira Kinoshita, Koh-Ichiro Yoshiura, Hiroko Ninomiya, Takeshi Imamura, Long Guo, Jingyi Xue, Li Yan, Hirofumi Ohashi, Yann Pretemer, Shunsuke Kawai, Masaaki Shiina, Kazuhiro Ogata, Daniel H Cohn, Naomichi Matsumoto, Gen Nishimura, Junya Toguchida, Noriko Miyake, Shiro Ikegawa

英文原著 Cellular senescence by loss of Men1 in osteoblasts is critical for age-related osteoporosis

Aging Cell.， 2024； 23(10)：e14254

DOI:10.1111/acel.14254

Yuichiro Ukon, Takashi Kaito, Hiromasa Hirai, Takayuki Kitahara, Masayuki Bun, Joe Kodama, Daisuke Tateiwa, Shinichi Nakagawa, Masato Ikuta, Takuya Furuichi, Yuya Kanie, Takahito Fujimori, Shota Takenaka, Tadashi Yamamuro, Satoru Otsuru, Seiji Okada, Masakatsu Yamashita, Takeshi Imamura

英文原著 Graded arc beam in light needle microscopy for axially resolved, rapid volumetric imaging without nonlinear processes

Opt Express.， 2024； 32(5)：7289-7306

DOI:10.1364/OE.516437

Daisuke Kume, Yuichi Kozawa, Ryosuke Kawakami, Hirokazu Ishii, Yuki Watakabe, Yuuki Uesugi, Takeshi Imamura, Tomomi Nemoto, Shunichi Sato

英文原著 A fluorescence imaging technique suggests that sweat leakage in the epidermis contributes to the pathomechanism of palmoplantar pustulosis

Sci Rep.， 2024； 14(1)：378

DOI:10.1038/s41598-023-50875-x

Kazuki Yatsuzuka, Ryosuke Kawakami, Yosuke Niko, Teruko Tsuda, Kenji Kameda, Nobushige Kohri, Satoshi Yoshida, Ken Shiraishi, Jun Muto, Hideki Mori, Yasuhiro Fujisawa, Takeshi Imamura, Masamoto Murakami

英文原著 Pyrene-fused dioxaborine-based merocyanines with high brightness, photostability, and fluorogenic function for deep-skin tissue imaging of a living mouse

BCSJ.， 2024； 97 (3)：uoad027

DOI:10.1093/bulcsj/uoad027

Haruka Nishihara, Mai Watanabe, Ryosuke Kawakami, Masamoto Murakami, Hitomi Seki, Katsuki Osaki, Teruko Tsuda, Takeshi Imamura, Shingo Hadano, Shigeru Watanabe, Yosuke Niko

英文原著 Advances in transmission-blocking vaccines against Plasmodium falciparum and Plasmodium vivax

Expert Review of Vaccines.， 2025； 24：509-523

DOI:10.1080/14760584.2025.2517720

Tachibana M, Takashima E, Torii M, Wu Y, Sattabongkot J, Tsuboi T

英文原著 Origin of the human malaria parasite Plasmodium vivax

Trends in Parasitology.， 2024； 40 (7)：562-572

DOI:10.1016/j.pt.2024.05.001

Sharp PM, Plenderleith LJ, Culleton RL, Hahn BH

英文原著 Integrative single cell multi-omics analysis captures a role of IRF8 as a gatekeeper for osteoclastogenesis

J Bone Miner Res.， 2025； 40(10)：1104-1105

DOI:10.1093/jbmr/zjaf103

Imai Y

英文原著 Differential effects of the D1/S264V mutation in Photosystem II with either PsbA1 or PsbA3 on QB, non-heme Iron, and the associated hydrogen-bond network

Biochim. Biophys. Acta (Bioenergetics).， 2025； 1866：149557

DOI:10.1016/j.bbabio.2025.149557

Tada, K., Yamagata, K., Koyama, K., Sellés, S., Boussac, A., and Sugiura, M.

英文原著 PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration

Nat Commun..， 2025； 16：3734

DOI:10.1038/s41467-025-59010-y

Goto A, Komura S, Kato K, Maki R, Hirakawa A, Aoki H, Tomita H, Taguchi J, Ozawa M, Matsushima T, Kishida A, Kimura T, Asahara H, Imai Y, Yamada Y, Akiyama H.

英文原著 The splicing factor Acin1 is essential for embryonic development but has limited effects on muscle structure and homeostasis

Scientific Reports..， 2025； 15：14017

DOI:10.1038/s41598-025-98851-x

Aoto M, Sakai H, Tokunaga N, Miyazaki M, Kiyoi T, Ohkubo N, Imai Y, Mitsuda N.

英文原著 Density and structure of DNA immobilised on gold nanoparticles affect sensitivity in nucleic acid detection

Sci. Rep..， 2025； 15：8222

DOI:10.1038/s41598-025-92474-y

Nanami Fukuzumi, Gen Hirao, Atsushi Ogawa, Tsuyoshi Asahi, Mizuo Maeda, Tamotsu Zako

英文原著 Cell-Free Multistep Gene Regulatory Cascades Using Eukaryotic ON-Riboswitches Responsive to in Situ Expressed Protein Ligands

ACS Synth. Biol..， 2025； 14：909-918

DOI:10.1021/acssynbio.4c00840

Atsushi Ogawa, Masahiro Fujikawa, Riku Tanimoto, Kiho Matsuno, Riko Uehara, Honami Inoue, Hajime Takahashi

英文原著 Effect of DNA Density on Nucleic Acid Detection Using Cross-Linking Aggregation of DNA-Modified Gold Nanoparticles

Langmuir.， 2025； 41：4560-4568

DOI:10.1021/acs.langmuir.4c04343

Yuki Tanaka, Gen Hirao, Nanami Fukuzumi, Tsuyoshi Asahi, Mizuo Maeda, Atsushi Ogawa, Tamotsu Zako

英文原著 New insights into the involvement of residue D1-V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus

Biochim. Biophys. Acta (Bioenergetics).， 2025； 1866：149550

DOI:10.1016/j.bbabio.2025.149550

Boussac, A., Sellés, J., Sugiura, M., and Burnap, R.L.

英文原著 Micrometer-sized liposomes self-aggregate by forming DNA duplexes on their surfaces more sensitively than metallic nanoparticles

Chem. Lett..， 2025； 54：upaf012

DOI:10.1093/chemle/upaf012

Atsushi Ogawa, Ichiro Enomoto, Hajime Takahashi

英文原著 HERC3 provides an ERAD branch for select membrane proteins by recognizing membrane-spanning domains.

J Cell Biol..， 2024； 223：e202308003

DOI:10.1083/jcb.202308003

Kamada Y, Ohnishi Y, Nakashima C, Fujii A, Terakawa M, Hamano I, Nakayamada U, Katoh S, Hirata N, Tateishi H, Fukuda R, Takahashi H, Lukacs GL, Okiyoneda T.

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