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英文原著 Biochemical and histological evidence of deteriorated bioprosthetic valve leaflets: the accumulation of fibrinogen and plasminogen.

Biol Open.., 2018; 7:bio034009
DOI:10.1242/bio.034009
Sakaue T, Nakaoka H, Shikata F, Aono J, Kurata M, Uetani T, Hamaguchi M, Kojima A, Uchita S, Yasugi T, Higashi H, Suzuki J, Ikeda S, Higaki J, Higashiyama S, Izutani H.

英文原著 IAPP/amylin deposition, which is correlated with expressions of ASC and IL-1β in β-cells of Langerhans’ islets, directly initiates NLRP3 inflammasome activation.

Int J Immunopathol Pharmacol.., 2018; 32:2.06E+15
DOI:10.1177/2058738418788749
Morikawa S, Kaneko N, Okumura C, Taguchi H, Kurata M, Yamamoto T, Osawa H, Nakanishi A, Zako T, Masumoto J.

英文原著 Combined morphological, immunohistochemical and genetic analyses of medulloepithelioma in the posterior cranial fossa.

Neuropathology.., 2018; 38:179-184
DOI:10.1111/neup.12431
Kusakabe K, Kohno S, Inoue A, Seno T, Yonezawa S, Moritani K, Mizuno Y, Kurata M, Kitazawa R, Tauchi H, Watanabe H, Iwata S, Hirato J, Kunieda T.

英文原著 MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway.

Rheumatology (Oxford)., 2018; 57:718-726
DOI:10.1093/rheumatology/kex451
Koga T, Migita K, Sato T, Sato S, Umeda M, Nonaka F, Fukui S, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Masumoto J, Agematsu K, Yachie A, Yoshiura KI, Eguchi K, Kawakami A.

英文原著 Musculoskeletal manifestations occur predominantly in patients with later-onset familial Mediterranean fever: Data from a multicenter, prospective national cohort study in Japan.

Arthritis Res Ther.., 2018; 20:Article number 257
DOI:10.1186/s13075-018-1738-1
Endo Y, Koga T, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri S, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Agematsu K, Yachie A, Masumoto J, Migita K, Kawakami A.

英文原著 Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: Identification of an intrinsic NLRP3 ligand in a cell-free system

Inflamm Regen., 2018; :
DOI:10.1186/s41232-018-0085-6
Nakanishi A, Kaneko N, Takeda H, Sawasaki T, Morikawa S, Zhou W, Kurata M, Yamamoto T, Akbar SMF, Zako T, Masumoto J.

英文原著 Treatment of chronic hepatitis B naïve patuents with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial)

Plos One.., 2018; 13:20201236
DOI:10.1371/journal.pone.0201236
Al Mahtab M, Akbar SMF, Aguilar JC, Guillen G, Penton E, Tuero A, Yoshida O, Hiasa Y, Onji M.

英文原著 Cerebral amyloid angiopathy-related inflammation with epilepsy mimicking a presentation of brain tumor: A case report and review of the literature.

Int J Surg Case Rep.., 2018; 48:95-100
DOI:10.1016/j.ijscr.2018.05.016
Kusakabe K, Inoue A, Matsumoto S, Kurata M, Kitazawa R, Watanabe H, Kunieda T.

英文原著 Comprehensive analysis of antibody responses to Plasmodium falciparum erythrocyte membrane protein 1 domains

Vaccine., 2018; 36:6826–6833
DOI:10.1016/j.vaccine.2018.08.058
Kanoi BN, Nagaoka H, Morita M, White MT, Palacpac NMQ, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T, Takashima E

英文原著 Mechanism of proton-coupled electron transfer in the S0-to-S1 transition of photosynthetic water oxidation as revealed by time-resolved infrared spectroscopy

J. Phys. Chem. B., 2018; 122:9460-9470
DOI:10.1021/acs.jpcb.8b07455
Shimizu, T. Sugiura, M., and Noguchi, T.

英文原著 Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes.

Front Pharmacol.., 2018; 9:38
DOI:10.3389/fphar.2018.00038
Suzuki Y, Ogasawara T, Tanaka Y, Takeda H, Sawasaki T, Mogi M, Liu S, Maeyama K.

英文原著 Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5.

Scientific Reports., 2018; 8:8383
DOI:10.1038/s41598-018-26560-9
Yosuke Hashimoto, Wei Zhou, Kohtaroh Hamauchi, Keisuke Shirakura, Takefumi Doi, Kiyohito Yagi, Tatsuya Sawasaki, Yoshiaki Okada, Masuo Kondoh, Hiroyuki Takeda

英文原著 Progress toward a transmission-blocking vaccine against malaria

Lancet Infect Dis.., 2018; 18:927-928
DOI:10.1016/S1473-3099(18)30358-X
Ishino T, Tsuboi T

英文原著 Plasmodium falciparum Exported Protein 1 is localized to dense granules in merozoites

Parasitol Int.., 2018; 67:637-639
DOI:10.1016/j.parint.2018.06.001
Iriko H, Ishino T, Otsuki H, Ito D, Tachibana M, Torii M, Tsuboi T

英文原著 Characterization of Plasmodium berghei Pbg37 as Both a Pre- and Postfertilization Antigen with Transmission-Blocking Potential

Infect Immun.., 2018; 86:e00785-17
DOI:10.1128/IAI.00785-17
Liu F, Li L, Zheng W, He Y, Wang Y, Zhu X, Tsuboi T, Cui L, Wang M, Cao Y

英文原著 The malaria parasite RhopH protein complex interacts with erythrocyte calmyrin identified from a comprehensive erythrocyte protein library

Biochem Biophys Res Commun.., 2018; 500:261-267
DOI:10.1016/j.bbrc.2018.04.056
Miura T, Takeo S, Ntege EH, Otsuki H, Sawasaki T, Ishino T, Takashima E, Tsuboi T

英文原著 Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5

Sci Rep.., 2018; 8:5052
DOI:10.1038/s41598-018-23194-9
Tougan T, Edula JR, Takashima E, Morita M, Shinohara M, Shinohara A, Tsuboi T, Horii T

英文原著 Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016

Emerg Infect Dis.., 2018; 24:718-726
DOI:10.3201/eid2404.170141
Ikeda M, Kaneko M, Tachibana SI, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Yamauchi M, Sekihara M, Hashimoto M, Katuro OT, Olia A, Obwoya PS, Auma MA, Anywar DA, Odongo-Aginya EI, Okello-Onen J, Hirai M, Ohashi J, Palacpac NMQ, Kataoka M, Tsuboi T, Kimura E, Horii T, Mita T

英文原著 PV1, a novel Plasmodium falciparum merozoite dense granule protein, interacts with exported protein in infected erythrocytes

Sci Rep.., 2018; 8:3696
DOI:10.1038/s41598-018-22026-0
Morita M, Nagaoka H, Ntege EH, Kanoi BN, Ito D, Nakata T, Lee JW, Tokunaga K, Iimura T, Torii M, Tsuboi T, Takashima E

英文原著 The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation

Nat Commun.., 2018; 9:3296
DOI:10.1038/s41467-018-05854-6
Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, Takemori A, Matsuda S, Kanoh M, Imai Y, Yasukawa M, Yamashita M.