Kanoi BN, Nagaoka H, Morita M, Tsuboi T, Takashima E. Leveraging the wheat germ cell-free protein synthesis system to accelerate malaria vaccine development. Parasitol Int. 2021 Feb;80:102224. doi: 10.1016/j.parint.2020.102224. Epub 2020 Oct 30. Review. PubMed PMID: 33137499.
72.
Nagaoka H, Kanoi BN, Morita M, Nakata T, Palacpac NMQ, Egwang TG, Horii T, Tsuboi T, Takashima E. Characterization of a Plasmodium falciparum PHISTc protein, PF3D7_0801000, in blood- stage malaria parasites. Parasitol Int. 2021 Feb;80:102240. doi: 10.1016/j.parint.2020.102240. Epub 2020 Nov 2. PubMed PMID: 33147497.
71.
Ito D, Chen JH, Takashima E, Hasegawa T, Otsuki H, Takeo S, Thongkukiatkul A, Han ET, Tsuboi T. Identification of a Novel RAMA/RON3 Rhoptry Protein Complex in Plasmodium falciparum Merozoites. Front Cell Infect Microbiol. 2020;10:605367. doi: 10.3389/fcimb.2020.605367. eCollection 2020. PubMed PMID: 33537242; PubMed Central PMCID: PMC7848174.
70.
Mazhari R, Brewster J, Fong R, Bourke C, Liu ZSJ, Takashima E, Tsuboi T, Tham WH, Harbers M, Chitnis C, Healer J, Ome-Kaius M, Sattabongkot J, Kazura J, Robinson LJ, King C, Mueller I, Longley RJ. A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against Plasmodium vivax antigens in a multiplexed bead-based assay using Luminex technology (Bio-Plex 200 or MAGPIX). PLoS One. 2020;15(12):e0238010. doi: 10.1371/journal.pone.0238010. eCollection 2020. PubMed PMID: 33275613; PubMed Central PMCID: PMC7717507.
69.
La TM, Tachibana H, Li SA, Abe T, Seiriki S, Nagaoka H, Takashima E, Takeda T, Ogawa D, Makino SI, Asanuma K, Watanabe M, Tian X, Ishibe S, Sakane A, Sasaki T, Wada J, Takei K, Yamada H. Dynamin 1 is important for microtubule organization and stabilization in glomerular podocytes. FASEB J. 2020 Dec;34(12):16449-16463. doi: 10.1096/fj.202001240RR. Epub 2020 Oct 17. PubMed PMID: 33070431.
68.
Hakamada K, Nakamura M, Midorikawa R, Shinohara K, Noguchi K, Nagaoka H, Takashima E, Morishima K, Inoue R, Sugiyama M, Kawamoto A, Yohda M. PV1 Protein from Plasmodium falciparum Exhibits Chaperone-Like Functions and Cooperates with Hsp100s. Int J Mol Sci. 2020 Nov 16;21(22). doi: 10.3390/ijms21228616. PubMed PMID: 33207549; PubMed Central PMCID: PMC7697860.
67.
Kondo Y, Ito D, Tademoto S, Itami N, Nishikata S, Takashima E, Tsuboi T, Fukumoto S, Otsuki H. Molecular cloning and characterization of plerocercoid-immunosuppressive factor from Spirometra erinaceieuropaei. Parasitol Int. 2020 Jun;76:102062. doi: 10.1016/j.parint.2020.102062. Epub 2020 Jan 21. PubMed PMID: 31978597.
66.
Kanoi BN, Nagaoka H, White MT, Morita M, Palacpac NMQ, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T, Takashima E. Global Repertoire of Human Antibodies Against Plasmodium falciparum RIFINs, SURFINs, and STEVORs in a Malaria Exposed Population. Front Immunol. 2020;11:893. doi: 10.3389/fimmu.2020.00893. eCollection 2020. PubMed PMID: 32477363; PubMed Central PMCID: PMC7235171.
65.
Longley RJ, White MT, Takashima E, Brewster J, Morita M, Harbers M, Obadia T, Robinson LJ, Matsuura F, Liu ZSJ, Li-Wai-Suen CSN, Tham WH, Healer J, Huon C, Chitnis CE, Nguitragool W, Monteiro W, Proietti C, Doolan DL, Siqueira AM, Ding XC, Gonzalez IJ, Kazura J, Lacerda M, Sattabongkot J, Tsuboi T, Mueller I. Development and validation of serological markers for detecting recent Plasmodium vivax infection. Nat Med. 2020 May;26(5):741-749. doi: 10.1038/s41591-020-0841-4. Epub 2020 May 11. PubMed PMID: 32405064.
64.
Nagaoka H, Kanoi BN, Ntege EH, Aoki M, Fukushima A, Tsuboi T, Takashima E. Antibodies against a short region of PfRipr inhibit Plasmodium falciparum merozoite invasion and PfRipr interaction with Rh5 and SEMA7A. Sci Rep. 2020 Apr 20;10(1):6573. doi: 10.1038/s41598-020-63611-6. PubMed PMID: 32313230; PubMed Central PMCID: PMC7171142.
63.
Tougan T, Edula JR, Morita M, Takashima E, Honma H, Tsuboi T, Horii T. The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity. Malar J. 2020 Apr 15;19(1):155. doi: 10.1186/s12936-020-03229-1. PubMed PMID: 32295584; PubMed Central PMCID: PMC7161009.
62.
Tachibana M, Baba M, Takashima E, Tsuboi T, Torii M, Ishino T. The C-terminal region of the Plasmodium yoelii microgamete surface antigen PyMiGS induces potent anti-malarial transmission-blocking immunity in mice. Vaccine. 2020 Mar 30;38(15):3129-3136. doi: 10.1016/j.vaccine.2020.02.058. Epub 2020 Mar 5. PubMed PMID: 32147299.
61.
Lee Y, Yamada H, Pradipta A, Ma JS, Okamoto M, Nagaoka H, Takashima E, Standley DM, Sasai M, Takei K, Yamamoto M. Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense. Life Sci Alliance. 2020 Jan;3(1). doi: 10.26508/lsa.201900549. Print 2020 Jan. PubMed PMID: 31852733; PubMed Central PMCID: PMC6925386.
60.
Nagaoka H, Kanoi BN, Jinoka K, Morita M, Arumugam TU, Palacpac NMQ, Egwang TG, Horii T, Tsuboi T, Takashima E. The N-Terminal Region of Plasmodium falciparum MSP10 Is a Target of Protective Antibodies in Malaria and Is Important for PfGAMA/PfMSP10 Interaction. Front Immunol. 2019;10:2669. doi: 10.3389/fimmu.2019.02669. eCollection 2019. PubMed PMID: 31824483; PubMed Central PMCID: PMC6880778.
59.
Miura K, Tachibana M, Takashima E, Morita M, Kanoi BN, Nagaoka H, Baba M, Torii M, Ishino T, Tsuboi T. Malaria transmission-blocking vaccines: wheat germ cell-free technology can accelerate vaccine development. Expert Rev Vaccines. 2019 Oct;18(10):1017-1027. doi: 10.1080/14760584.2019.1674145. Epub 2019 Oct 10. Review. PubMed PMID: 31566026.
58.
Nagaoka H, Sasaoka C, Yuguchi T, Kanoi BN, Ito D, Morita M, Udomsangpetch R, Sattabongkot J, Ishino T, Tsuboi T, Takashima E. PfMSA180 is a novel Plasmodium falciparum vaccine antigen that interacts with human erythrocyte integrin associated protein (CD47). Sci Rep. 2019 Apr 11;9(1):5923. doi: 10.1038/s41598-019-42366-9. PubMed PMID: 30976034; PubMed Central PMCID: PMC6459815.
57.
Yusuf Y, Yoshii T, Iyori M, Yoshida K, Mizukami H, Fukumoto S, Yamamoto DS, Alam A, Emran TB, Amelia F, Islam A, Otsuka H, Takashima E, Tsuboi T, Yoshida S. Adeno-Associated Virus as an Effective Malaria Booster Vaccine Following Adenovirus Priming. Front Immunol. 2019;10:730. doi: 10.3389/fimmu.2019.00730. eCollection 2019. PubMed PMID: 31024558; PubMed Central PMCID: PMC6460511.
56.
Tohmoto T, Takashima E, Takeo S, Morita M, Nagaoka H, Udomsangpetch R, Sattabongkot J, Ishino T, Torii M, Tsuboi T. Anti-MSP11 IgG inhibits Plasmodium falciparum merozoite invasion into erythrocytes in vitro. Parasitol Int. 2019 Apr;69:25-29. doi: 10.1016/j.parint.2018.10.012. Epub 2018 Oct 30. PubMed PMID: 30385417.
55.
Genomic and biological features of Plasmodium falciparum resistance against antimalarial endoperoxide N-89.
Morita M, Hayashi K, Sato A, Hiramoto A, Kaneko O, Isogawa R, Kurosaki Y, Miyoshi SI, Chang KS, Wataya Y, Kim HS.
Gene. 2019 Oct 20;716:144016. doi: 10.1016/j.gene.2019.144016. Epub 2019 Aug 1.
PMID: 31377318
54.
Tachibana M, Miura K, Takashima E, Morita M, Nagaoka H, Zhou L, Long CA, Richter King C, Torii M, Tsuboi T, Ishino T. Identification of domains within Pfs230 that elicit transmission blocking antibody responses. Vaccine. 2019 Mar 22;37(13):1799-1806. doi: 10.1016/j.vaccine.2019.02.021. Epub 2019 Feb 26. PubMed PMID: 30824357; PubMed Central PMCID: PMC6708081.
53.
Reiling L, Boyle MJ, White MT, Wilson DW, Feng G, Weaver R, Opi DH, Persson KEM, Richards JS, Siba PM, Fowkes FJI, Takashima E, Tsuboi T, Mueller I, Beeson JG. Targets of complement-fixing antibodies in protective immunity against malaria in children. Nat Commun. 2019 Feb 5;10(1):610. doi: 10.1038/s41467-019-08528-z. PubMed PMID: 30723225; PubMed Central PMCID: PMC6363798.
52.
Ito D, Takashima E, Yamasaki T, Hatano S, Hasegawa T, Miura K, Morita M, Thongkukiatkul A, Diakite M, Long CA, Sattabongkot J, Udomsangpetch R, Iriko H, Ishino T, Tsuboi T. Antibodies against a Plasmodium falciparum RON12 inhibit merozoite invasion into erythrocytes. Parasitol Int. 2019 Feb;68(1):87-91. doi: 10.1016/j.parint.2018.10.006. Epub 2018 Oct 17. PubMed PMID: 30342119; PubMed Central PMCID: PMC6688612.
51.
Kanoi BN, Nagaoka H, Morita M, White MT, Palacpac NMQ, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T, Takashima E. Comprehensive analysis of antibody responses to Plasmodium falciparum erythrocyte membrane protein 1 domains. Vaccine. 2018 Oct 29;36(45):6826-6833. doi: 10.1016/j.vaccine.2018.08.058. Epub 2018 Sep 24. PubMed PMID: 30262245.
50.
Miura T, Takeo S, Ntege EH, Otsuki H, Sawasaki T, Ishino T, Takashima E, Tsuboi T. The malaria parasite RhopH protein complex interacts with erythrocyte calmyrin identified from a comprehensive erythrocyte protein library. Biochem Biophys Res Commun. 2018 Jun 2;500(2):261-267. doi: 10.1016/j.bbrc.2018.04.056. Epub 2018 Apr 13. PubMed PMID: 29653104.
49.
Tachibana M, Ishino T, Takashima E, Tsuboi T, Torii M. A male gametocyte osmiophilic body and microgamete surface protein of the rodent malaria parasite Plasmodium yoelii (PyMiGS) plays a critical role in male osmiophilic body formation and exflagellation. Cell Microbiol. 2018 May;20(5):e12821. doi: 10.1111/cmi.12821. Epub 2018 Jan 23. PubMed PMID: 29316140; PubMed Central PMCID: PMC5901010.
48.
Sakamoto H, Takeo S, Takashima E, Miura K, Kanoi BN, Kaneko T, Han ET, Tachibana M, Matsuoka K, Sattabongkot J, Udomsangpetch R, Ishino T, Tsuboi T. Identification of target proteins of clinical immunity to Plasmodium falciparum in a region of low malaria transmission. Parasitol Int. 2018 Apr;67(2):203-208. doi: 10.1016/j.parint.2017.12.002. Epub 2017 Dec 5. PubMed PMID: 29217416; PubMed Central PMCID: PMC6343659.
47.
Tougan T, Edula JR, Takashima E, Morita M, Shinohara M, Shinohara A, Tsuboi T, Horii T. Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5. Sci Rep. 2018 Mar 22;8(1):5052. doi: 10.1038/s41598-018-23194-9. PubMed PMID: 29567995; PubMed Central PMCID: PMC5864917.
46.
Morita M, Nagaoka H, Ntege EH, Kanoi BN, Ito D, Nakata T, Lee JW, Tokunaga K, Iimura T, Torii M, Tsuboi T, Takashima E. PV1, a novel Plasmodium falciparum merozoite dense granule protein, interacts with exported protein in infected erythrocytes. Sci Rep. 2018 Feb 27;8(1):3696. doi: 10.1038/s41598-018-22026-0. PubMed PMID: 29487358; PubMed Central PMCID: PMC5829233.
45.
Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H. Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors. Nature. 2017 Dec 7;552(7683):101-105. doi: 10.1038/nature24994. Epub 2017 Nov 29. PubMed PMID: 29186116; PubMed Central PMCID: PMC5748893.
44.
Franรงa CT, White MT, He WQ, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, Chitnis C, Cowman AF, Takashima E, Tsuboi T, Tham WH, Fairhurst RM, Rayner JC, King CL, Mueller I. Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development. Elife. 2017 Sep 26;6. doi: 10.7554/eLife.28673. PubMed PMID: 28949293; PubMed Central PMCID: PMC5655538.
43.
Longley RJ, White MT, Takashima E, Morita M, Kanoi BN, Li Wai Suen CSN, Betuela I, Kuehn A, Sripoorote P, Franca CT, Siba P, Robinson LJ, Lacerda M, Sattabongkot J, Tsuboi T, Mueller I. Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions. PLoS Negl Trop Dis. 2017 Sep;11(9):e0005888. doi: 10.1371/journal.pntd.0005888. eCollection 2017 Sep. PubMed PMID: 28892517; PubMed Central PMCID: PMC5614652.
42.
Ntege EH, Takashima E, Morita M, Nagaoka H, Ishino T, Tsuboi T. Blood-stage malaria vaccines: post-genome strategies for the identification of novel vaccine candidates. Expert Rev Vaccines. 2017 Aug;16(8):769-779. doi: 10.1080/14760584.2017.1341317. Epub 2017 Jun 19. Review. PubMed PMID: 28604122.
41.
Morita M, Takashima E, Ito D, Miura K, Thongkukiatkul A, Diouf A, Fairhurst RM, Diakite M, Long CA, Torii M, Tsuboi T. Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate. Sci Rep. 2017 Apr 5;7:46086. doi: 10.1038/srep46086. PubMed PMID: 28378857; PubMed Central PMCID: PMC5380959.
40.
Muh F, Han JH, Nyunt MH, Lee SK, Jeon HY, Ha KS, Park WS, Hong SH, Ahmed MA, Na S, Takashima E, Tsuboi T, Han ET. Identification of a novel merozoite surface antigen of Plasmodium vivax, PvMSA180. Malar J. 2017 Mar 28;16(1):133. doi: 10.1186/s12936-017-1760-9. PubMed PMID: 28351409; PubMed Central PMCID: PMC5369000.
39.
Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O’Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ. Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3515-3520. doi: 10.1073/pnas.1615875114. Epub 2017 Mar 13. PubMed PMID: 28289193; PubMed Central PMCID: PMC5380044.
38.
Kanoi BN, Takashima E, Morita M, White MT, Palacpac NM, Ntege EH, Balikagala B, Yeka A, Egwang TG, Horii T, Tsuboi T. Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda. Vaccine. 2017 Feb 7;35(6):873-881. doi: 10.1016/j.vaccine.2017.01.001. Epub 2017 Jan 12. PubMed PMID: 28089547.
37.
Balikagala B, Mita T, Ikeda M, Sakurai M, Yatsushiro S, Takahashi N, Tachibana SI, Auma M, Ntege EH, Ito D, Takashima E, Palacpac NM, Egwang TG, Onen JO, Kataoka M, Kimura E, Horii T, Tsuboi T. Absence of in vivo selection for K13 mutations after artemether-lumefantrine treatment in Uganda. Malar J. 2017 Jan 9;16(1):23. doi: 10.1186/s12936-016-1663-1. PubMed PMID: 28068997; PubMed Central PMCID: PMC5223472.
36.
Ntege EH, Arisue N, Ito D, Hasegawa T, Palacpac NMQ, Egwang TG, Horii T, Takashima E, Tsuboi T. Identification of Plasmodium falciparum reticulocyte binding protein homologue 5-interacting protein, PfRipr, as a highly conserved blood-stage malaria vaccine candidate. Vaccine. 2016 Nov 4;34(46):5612-5622. doi: 10.1016/j.vaccine.2016.09.028. Epub 2016 Sep 28. PubMed PMID: 27692771.
35.
Cheng Y, Lu F, Wang B, Li J, Han JH, Ito D, Kong DH, Jiang L, Wu J, Ha KS, Takashima E, Sattabongkot J, Cao J, Nyunt MH, Kyaw MP, Desai SA, Miller LH, Tsuboi T, Han ET. Plasmodium vivax GPI-anchored micronemal antigen (PvGAMA) binds human erythrocytes independent of Duffy antigen status. Sci Rep. 2016 Oct 19;6:35581. doi: 10.1038/srep35581. PubMed PMID: 27759110; PubMed Central PMCID: PMC5069673.
34.
Duffy MF, Noviyanti R, Tsuboi T, Feng ZP, Trianty L, Sebayang BF, Takashima E, Sumardy F, Lampah DA, Turner L, Lavstsen T, Fowkes FJ, Siba P, Rogerson SJ, Theander TG, Marfurt J, Price RN, Anstey NM, Brown GV, Papenfuss AT. Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria. Malar J. 2016 May 5;15(1):258. doi: 10.1186/s12936-016-1296-4. PubMed PMID: 27149991; PubMed Central PMCID: PMC4858840.
33.
Takashima E, Morita M, Tsuboi T. Vaccine candidates for malaria: what’s new?. Expert Rev Vaccines. 2016;15(1):1-3. doi: 10.1586/14760584.2016.1112744. Epub 2015 Nov 11. PubMed PMID: 26559316.
32.
Mitri C, Bischoff E, Takashima E, Williams M, Eiglmeier K, Pain A, Guelbeogo WM, Gneme A, Brito-Fravallo E, Holm I, Lavazec C, Sagnon N, Baxter RH, Riehle MM, Vernick KD. An Evolution-Based Screen for Genetic Differentiation between Anopheles Sister Taxa Enriches for Detection of Functional Immune Factors. PLoS Pathog. 2015 Dec;11(12):e1005306. doi: 10.1371/journal.ppat.1005306. eCollection 2015 Dec. PubMed PMID: 26633695; PubMed Central PMCID: PMC4669117.
31
Nagaoka H, Nishiwaki H, Kubo T, Akamatsu M, Yamauchi S, Shuto Y. Docking model of the nicotinic acetylcholine receptor and nitromethylene neonicotinoid derivatives with a longer chiral substituent and their biological activities. Bioorg Med Chem. 2015 Feb 15;23(4):759-69. doi: 10.1016/j.bmc.2014.12.058. Epub 2015 Jan 3. PMID: 25618596.
30
Morita M, Koyama T, Sanai H, Sato A, Hiramoto A, Masuyama A, Nojima M, Wataya Y, Kim HS. Stage specific activity of synthetic antimalarial endoperoxides, N-89 and N-251, against Plasmodium falciparum. Parasitol Int. 2015 Feb;64(1):113-7. doi: 10.1016/j.parint.2014.10.007. Epub 2014 Oct 27. PMID: 25449979.
29.
Tsuboi T, Takashima E. Antibody titre as a surrogate of protection of the first malaria subunit vaccine, RTS,S/AS01. Lancet Infect Dis. 2015 Dec;15(12):1371-2. doi: 10.1016/S1473-3099(15)00300-X. Epub 2015 Sep 2. PubMed PMID: 26342425.
28.
Wang B, Lu F, Cheng Y, Chen JH, Jeon HY, Ha KS, Cao J, Nyunt MH, Han JH, Lee SK, Kyaw MP, Sattabongkot J, Takashima E, Tsuboi T, Han ET. Immunoprofiling of the tryptophan-rich antigen family in Plasmodium vivax. Infect Immun. 2015 Aug;83(8):3083-95. doi: 10.1128/IAI.03067-14. Epub 2015 May 18. PubMed PMID: 25987709; PubMed Central PMCID: PMC4496608.
27
Palacpac NM, Ntege E, Balikagala B, Yeka A, Shirai H, Suzuki N, Nsereko C, Kanoi BN, Okada T, Egwang TG, Horii T. Hematological and biochemical data obtained in rural northern Uganda. Int J Environ Res Public Health. 2014 May 6;11(5):4870-85. doi: 10.3390/ijerph110504870. PMID: 24806194; PMCID: PMC4053919.
26.
Arumugam TU, Ito D, Takashima E, Tachibana M, Ishino T, Torii M, Tsuboi T. Application of wheat germ cell-free protein expression system for novel malaria vaccine candidate discovery. Expert Rev Vaccines. 2014 Jan;13(1):75-85. doi: 10.1586/14760584.2014.861747. Epub 2013 Dec 5. Review. PubMed PMID: 24308585.
25
Palacpac NM, Ntege E, Yeka A, Balikagala B, Suzuki N, Shirai H, Yagi M, Ito K, Fukushima W, Hirota Y, Nsereko C, Okada T, Kanoi BN, Tetsutani K, Arisue N, Itagaki S, Tougan T, Ishii KJ, Ueda S, Egwang TG, Horii T. Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36. PLoS One. 2013 May 28;8(5):e64073. doi: 10.1371/journal.pone.0064073. PMID: 23724021; PMCID: PMC3665850.
24.
Miura K, Takashima E, Deng B, Tullo G, Diouf A, Moretz SE, Nikolaeva D, Diakite M, Fairhurst RM, Fay MP, Long CA, Tsuboi T. Functional comparison of Plasmodium falciparum transmission-blocking vaccine candidates by the standard membrane-feeding assay. Infect Immun. 2013 Dec;81(12):4377-82. doi: 10.1128/IAI.01056-13. Epub 2013 Sep 16. PubMed PMID: 24042109; PubMed Central PMCID: PMC3838000.
23.
Mathias DK, Pastrana-Mena R, Ranucci E, Tao D, Ferruti P, Ortega C, Staples GO, Zaia J, Takashima E, Tsuboi T, Borg NA, Verotta L, Dinglasan RR. A small molecule glycosaminoglycan mimetic blocks Plasmodium invasion of the mosquito midgut. PLoS Pathog. 2013;9(11):e1003757. doi: 10.1371/journal.ppat.1003757. Epub 2013 Nov 21. PubMed PMID: 24278017; PubMed Central PMCID: PMC3836724.
22.
Ito D, Hasegawa T, Miura K, Yamasaki T, Arumugam TU, Thongkukiatkul A, Takeo S, Takashima E, Sattabongkot J, Han ET, Long CA, Torii M, Tsuboi T. RALP1 is a rhoptry neck erythrocyte-binding protein of Plasmodium falciparum merozoites and a potential blood-stage vaccine candidate antigen. Infect Immun. 2013 Nov;81(11):4290-8. doi: 10.1128/IAI.00690-13. Epub 2013 Sep 3. PubMed PMID: 24002067; PubMed Central PMCID: PMC3811813.
21.
Cheng Y, Wang Y, Ito D, Kong DH, Ha KS, Chen JH, Lu F, Li J, Wang B, Takashima E, Sattabongkot J, Tsuboi T, Han ET. The Plasmodium vivax merozoite surface protein 1 paralog is a novel erythrocyte-binding ligand of P. vivax. Infect Immun. 2013 May;81(5):1585-95. doi: 10.1128/IAI.01117-12. Epub 2013 Mar 4. PubMed PMID: 23460511; PubMed Central PMCID: PMC3648005.
20.
Holm I, Lavazec C, Garnier T, Mitri C, Riehle MM, Bischoff E, Brito-Fravallo E, Takashima E, Thiery I, Zettor A, Petres S, Bourgouin C, Vernick KD, Eiglmeier K. Diverged alleles of the Anopheles gambiae leucine-rich repeat gene APL1A display distinct protective profiles against Plasmodium falciparum. PLoS One. 2012;7(12):e52684. doi: 10.1371/journal.pone.0052684. Epub 2012 Dec 28. PubMed PMID: 23285147; PubMed Central PMCID: PMC3532451.
19
Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, Sakura T, Kaneko O, Masuyama A, Nojima M, Wataya Y, Kim HS. Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251. J Proteome Res. 2012 Dec 7;11(12):5704-11. doi: 10.1021/pr3005315. Epub 2012 Oct 25. PMID: 23061985.
18
Nishiwaki H, Kuriyama M, Nagaoka H, Kato A, Akamatsu M, Yamauchi S, Shuto Y. Synthesis of imidacloprid derivatives with a chiral alkylated imidazolidine ring and evaluation of their insecticidal activity and affinity to the nicotinic acetylcholine receptor. Bioorg Med Chem. 2012 Nov 1;20(21):6305-12. doi: 10.1016/j.bmc.2012.09.007. Epub 2012 Sep 13. PMID: 23026081.
17
Proietti C, Pettinato DD, Kanoi BN, Ntege E, Crisanti A, Riley EM, Egwang TG, Drakeley C, Bousema T. Continuing intense malaria transmission in northern Uganda. Am J Trop Med Hyg. 2011 May;84(5):830-7. doi: 10.4269/ajtmh.2011.10-0498. PMID: 21540398; PMCID: PMC3083756.
16
Sato A, Kawai S, Hiramoto A, Morita M, Tanigawa N, Nakase Y, Komichi Y, Matsumoto M, Hiraoka O, Hiramoto K, Tokuhara H, Masuyama A, Nojima M, Higaki K, Hayatsu H, Wataya Y, Kim HS. Antimalarial activity of 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) and its carboxylic acid derivatives. Parasitol Int. 2011 Dec;60(4):488-92. doi: 10.1016/j.parint.2011.08.017. Epub 2011 Sep 8. PMID: 21924377.
15
Nishiwaki H, Nagaoka H, Kuriyama M, Yamauchi S, Shuto Y. Affinity to the nicotinic acetylcholine receptor and insecticidal activity of chiral imidacloprid derivatives with a methylated imidazolidine ring. Biosci Biotechnol Biochem. 2011;75(4):780-2. doi: 10.1271/bbb.100846. Epub 2011 Apr 22. PMID: 21512232.
14
Sato A, Hiramoto A, Morita M, Matsumoto M, Komich Y, Nakase Y, Tanigawa N, Hiraoka O, Hiramoto K, Hayatsu H, Higaki K, Kawai S, Masuyama A, Nojima M, Wataya Y, Kim HS. Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol. Parasitol Int. 2011 Sep;60(3):270-3. doi: 10.1016/j.parint.2011.04.001. Epub 2011 Apr 8. PMID: 21501696.
13.
Takashima E, Yamada H, Yajima A, Shiomi K, Omura S, Kiyoshi K. A quinol peroxidase inhibitor prevents secretion of a leukotoxin from Aggregatibacter actinomycetemcomitans. J Periodontal Res. 2010 Feb;45(1):123-8. doi: 10.1111/j.1600-0765.2009.01211.x. Epub 2009 Jul 8. PubMed PMID: 19602106.
12
Takashima E, Yamada H, Yamashita T, Matsushita K, Konishi K. Recombinant expression and redox properties of triheme c membrane-bound quinol peroxidase. FEMS Microbiol Lett. 2010 Jan;302(1):52-7. doi: 10.1111/j.1574-6968.2009.01830.x. Epub 2009 Oct 22. PubMed PMID: 19895641.
11.
Morales J, Mogi T, Mineki S, Takashima E, Mineki R, Hirawake H, Sakamoto K, Omura S, Kita K. Novel mitochondrial complex II isolated from Trypanosoma cruzi is composed of 12 peptides including a heterodimeric Ip subunit. J Biol Chem. 2009 Mar 13;284(11):7255-63. doi: 10.1074/jbc.M806623200. Epub 2009 Jan 2. PubMed PMID: 19122194; PubMed Central PMCID: PMC2652292.
10.
Urano-Tashiro Y, Yajima A, Takashima E, Takahashi Y, Konishi K. Binding of the Streptococcus gordonii DL1 surface protein Hsa to the host cell membrane glycoproteins CD11b, CD43, and CD50. Infect Immun. 2008 Oct;76(10):4686-91. doi: 10.1128/IAI.00238-08. Epub 2008 Aug 4. PubMed PMID: 18678668; PubMed Central PMCID: PMC2546842.
9.
Takashima E, Konishi K. Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans. FEMS Microbiol Lett. 2008 Sep;286(1):66-70. doi: 10.1111/j.1574-6968.2008.01253.x. PubMed PMID: 18616592.
8.
Shimazu K, Takahashi Y, Uchikawa Y, Shimazu Y, Yajima A, Takashima E, Aoba T, Konishi K. Identification of the Streptococcus gordonii glmM gene encoding phosphoglucosamine mutase and its role in bacterial cell morphology, biofilm formation, and sensitivity to antibiotics. FEMS Immunol Med Microbiol. 2008 Jul;53(2):166-77. doi: 10.1111/j.1574-695X.2008.00410.x. Epub 2008 May 6. PubMed PMID: 18462386.
7.
Yajima A, Urano-Tashiro Y, Shimazu K, Takashima E, Takahashi Y, Konishi K. Hsa, an adhesin of Streptococcus gordonii DL1, binds to alpha2-3-linked sialic acid on glycophorin A of the erythrocyte membrane. Microbiol Immunol. 2008 Feb;52(2):69-77. doi: 10.1111/j.1348-0421.2008.00015.x. PubMed PMID: 18380804. Kanoi BN, Egwang TG. New concepts in vaccine development in malaria. Curr Opin Infect Dis. 2007 Jun;20(3):311-6. doi: 10.1097/QCO.0b013e32816b5cc2. PMID: 17471043.
6.
Yamada H, Takashima E, Konishi K. Molecular characterization of the membrane-bound quinol peroxidase functionally connected to the respiratory chain. FEBS J. 2007 Feb;274(3):853-66. doi: 10.1111/j.1742-4658.2006.05637.x. PubMed PMID: 17288564.
5.
Takahashi Y, Takashima E, Shimazu K, Yagishita H, Aoba T, Konishi K. Contribution of sialic acid-binding adhesin to pathogenesis of experimental endocarditis caused by Streptococcus gordonii DL1. Infect Immun. 2006 Jan;74(1):740-3. doi: 10.1128/IAI.74.1.740-743.2006. PubMed PMID: 16369032; PubMed Central PMCID: PMC1346603.
4.
Inaoka DK, Takashima E, Osanai A, Shimizu H, Nara T, Aoki T, Harada S, Kita K. Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt 10):875-8. doi: 10.1107/S174430910502659X. Epub 2005 Sep 13. PubMed PMID: 16511183; PubMed Central PMCID: PMC1991314.
3.
Mi-Ichi F, Takeo S, Takashima E, Kobayashi T, Kim HS, Wataya Y, Matsuda A, Torrii M, Tsuboi T, Kita K. Unique properties of respiratory chain in Plasmodium falciparum mitochondria. Adv Exp Med Biol. 2003;531:117-33. doi: 10.1007/978-1-4615-0059-9_9. Review. PubMed PMID: 12916785.
2.
Takashima E, Inaoka DK, Osanai A, Nara T, Odaka M, Aoki T, Inaka K, Harada S, Kita K. Characterization of the dihydroorotate dehydrogenase as a soluble fumarate reductase in Trypanosoma cruzi. Mol Biochem Parasitol. 2002 Jul;122(2):189-200. doi: 10.1016/s0166-6851(02)00100-7. PubMed PMID: 12106873.
1.
Takashima E, Takamiya S, Takeo S, Mi-ichi F, Amino H, Kita K. Isolation of mitochondria from Plasmodium falciparum showing dihydroorotate dependent respiration. Parasitol Int. 2001 Nov;50(4):273-8. doi: 10.1016/s1383-5769(01)00085-x. PubMed PMID: 11719114.
